Investigating the impact of regulatory B cells and regulatory B cell-related genes on bladder cancer progression and immunotherapeutic sensitivity

Investigating the impact of regulatory B cells and regulatory B cell-related genes on bladder cancer progression and immunotherapeutic sensitivity

Abstract Background Regulatory B cells (Bregs), a specialized subset of B cells that modulate immune responses and maintain immune tolerance in malignant tumors, have not been extensively investigated in the context of bladder cancer (BLCA). This study aims to elucidate the roles of Bregs and Breg-r...

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Bibliographic Details
Main Authors: Jiawei Zhou, Ranran Zhou, Yuanchao Zhu, Shikai Deng, Bahaerguli Muhuitijiang, Chengyao Li, Xiaojun Shi, Ling Zhang, Wanlong Tan
Format: Article
Language:English
Published: BMC 2024-04-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Bladder cancer
Regulatory B cells
Gene signature
Prognosis
Immunotherapy
Online Access:https://doi.org/10.1186/s13046-024-03017-8

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