A Lipidomic Analysis of Docosahexaenoic Acid (22:6, ω3) Mediated Attenuation of Western Diet Induced Nonalcoholic Steatohepatitis in Male <i>Ldlr <sup>-/-</sup></i> Mice

A Lipidomic Analysis of Docosahexaenoic Acid (22:6, ω3) Mediated Attenuation of Western Diet Induced Nonalcoholic Steatohepatitis in Male <i>Ldlr <sup>-/-</sup></i> Mice

Nonalcoholic fatty liver disease (NAFLD) is a major public health problem worldwide. NAFLD ranges in severity from benign steatosis to nonalcoholic steatohepatitis (NASH), cirrhosis, and primary hepatocellular cancer (HCC). Obesity and type 2 diabetes mellitus (T2DM) are strongly associated with NAF...

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Bibliographic Details
Main Authors:	Manuel García-Jaramillo, Kelli A. Lytle, Melinda H. Spooner, Donald B. Jump
Format:	Article
Language:	English
Published:	MDPI AG 2019-10-01
Series:	Metabolites
Subjects:	nonalcoholic fatty liver disease nonalcoholic steatohepatitis arachidonic acid docosahexaenoic acid inflammation fibrosis lipidomics mass spectrometry
Online Access:	https://www.mdpi.com/2218-1989/9/11/252

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