Effective Anti-tumor Response by TIGIT Blockade Associated With FcγR Engagement and Myeloid Cell Activation

The molecule “T cell immunoreceptor with immunoglobulin and ITIM domain,” or TIGIT, has recently received much attention as a promising target in the treatment of various malignancies. In spite of the quick progression of anti-TIGIT antibodies into clinical testing both as monotherapy and in combina...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Jin-Hwan Han, Mingmei Cai, Jeffery Grein, Samanthi Perera, Hongmei Wang, Mike Bigler, Roenna Ueda, Thomas W. Rosahl, Elaine Pinheiro, Drake LaFace, Wolfgang Seghezzi, Sybil M. Genther Williams
Формат: Өгүүллэг
Хэл сонгох:English
Хэвлэсэн: Frontiers Media S.A. 2020-10-01
Цуврал:Frontiers in Immunology
Нөхцлүүд:
Онлайн хандалт:https://www.frontiersin.org/article/10.3389/fimmu.2020.573405/full