Adequacy of surgical margins in oral cancer patients with respect to various types of reconstruction
Bacground: Surgical margin is an important prognostic factor for oral cancers (oral squamous cell carcinoma [OSCC]). The correlation of margin with the type of reconstruction has never been studied. Aim: This study aimed to correlate surgical margins with the type of reconstruction. Methods: This wa...
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
2020-01-01
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| Series: | South Asian Journal of Cancer |
| Subjects: | |
| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.4103/sajc.sajc_366_18 |
| _version_ | 1818387790018117632 |
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| author | Apurva Garg Manish Mair Hitesh Singhavi Muddasir Bhati Akshat Malik Aseem Mishra Deepa Nair Sudhir Nair Pankaj Chaturvedi |
| author_facet | Apurva Garg Manish Mair Hitesh Singhavi Muddasir Bhati Akshat Malik Aseem Mishra Deepa Nair Sudhir Nair Pankaj Chaturvedi |
| author_sort | Apurva Garg |
| collection | DOAJ |
| description | Bacground: Surgical margin is an important prognostic factor for oral cancers (oral squamous cell carcinoma [OSCC]). The correlation of margin with the type of reconstruction has never been studied. Aim: This study aimed to correlate surgical margins with the type of reconstruction. Methods: This was a retrospective study of 410 treatment-naïve OSCC patients. As per the methods of reconstruction, three groups were made when reconstruction was performed using pedicled flap (PF) or local flap, free flap, and primary closure (PC). Statistical Analysis: Chi-square test was used for comparison of margin status as per the method of reconstruction. Mann–Whitney test was used to find the difference between the mean margin width with respect to the type of reconstruction. Results: The overall incidence of close/positive margins was 7.8%. The incidence of close/positive margins was not significantly different in free flap group compared to PF (P = 0.06) or PC (P = 0.835) group. However, there was a significant difference in the incidence of close/positive margins between PC and PF groups (P = 0.021). Whether the reconstruction is performed by the primary surgeon or by a another surgeon, it did not have an impact on adequacy of margins (P = 0.334). Margins were wider when the reconstruction is performed by a different team (P = 0.015) or when reconstruction is performed as compared to PC. Conclusion: Margins are not affected by the type of reconstruction (pedicled vs. free flap) and the team doing reconstruction (same vs. another team). Margins are significantly compromised when a surgeon performs PC himself/herself compared to PF. |
| first_indexed | 2024-12-14T04:15:32Z |
| format | Article |
| id | doaj.art-95adc8e3b36c492ab7422679f9055aee |
| institution | Directory Open Access Journal |
| issn | 2278-330X 2278-4306 |
| language | English |
| last_indexed | 2024-12-14T04:15:32Z |
| publishDate | 2020-01-01 |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | South Asian Journal of Cancer |
| spelling | doaj.art-95adc8e3b36c492ab7422679f9055aee2022-12-21T23:17:33ZengThieme Medical and Scientific Publishers Pvt. Ltd.South Asian Journal of Cancer2278-330X2278-43062020-01-010901343710.4103/sajc.sajc_366_18Adequacy of surgical margins in oral cancer patients with respect to various types of reconstructionApurva Garg0Manish Mair1Hitesh Singhavi2Muddasir Bhati3Akshat Malik4Aseem Mishra5Deepa Nair6Sudhir Nair7Pankaj Chaturvedi8Department of Head and Neck Oncology, Tata Memorial Hospital, Mumbai, MaharashtraDepartment of Head and Neck Oncology, Tata Memorial Hospital, Mumbai, MaharashtraDepartment of Head and Neck Oncology, Tata Memorial Hospital, Mumbai, MaharashtraDepartment of Head and Neck Oncology, Tata Memorial Hospital, Mumbai, MaharashtraDepartment of Head and Neck Oncology, Tata Memorial Hospital, Mumbai, MaharashtraDepartment of Head and Neck Oncology, Tata Memorial Hospital, Mumbai, MaharashtraDepartment of Head and Neck Oncology, Tata Memorial Hospital, Mumbai, MaharashtraDepartment of Head and Neck Oncology, Tata Memorial Hospital, Mumbai, MaharashtraDepartment of Head and Neck Oncology, Tata Memorial Hospital, Mumbai, MaharashtraBacground: Surgical margin is an important prognostic factor for oral cancers (oral squamous cell carcinoma [OSCC]). The correlation of margin with the type of reconstruction has never been studied. Aim: This study aimed to correlate surgical margins with the type of reconstruction. Methods: This was a retrospective study of 410 treatment-naïve OSCC patients. As per the methods of reconstruction, three groups were made when reconstruction was performed using pedicled flap (PF) or local flap, free flap, and primary closure (PC). Statistical Analysis: Chi-square test was used for comparison of margin status as per the method of reconstruction. Mann–Whitney test was used to find the difference between the mean margin width with respect to the type of reconstruction. Results: The overall incidence of close/positive margins was 7.8%. The incidence of close/positive margins was not significantly different in free flap group compared to PF (P = 0.06) or PC (P = 0.835) group. However, there was a significant difference in the incidence of close/positive margins between PC and PF groups (P = 0.021). Whether the reconstruction is performed by the primary surgeon or by a another surgeon, it did not have an impact on adequacy of margins (P = 0.334). Margins were wider when the reconstruction is performed by a different team (P = 0.015) or when reconstruction is performed as compared to PC. Conclusion: Margins are not affected by the type of reconstruction (pedicled vs. free flap) and the team doing reconstruction (same vs. another team). Margins are significantly compromised when a surgeon performs PC himself/herself compared to PF.http://www.thieme-connect.de/DOI/DOI?10.4103/sajc.sajc_366_18free flapmarginsoral cancersprimary closurereconstruction |
| spellingShingle | Apurva Garg Manish Mair Hitesh Singhavi Muddasir Bhati Akshat Malik Aseem Mishra Deepa Nair Sudhir Nair Pankaj Chaturvedi Adequacy of surgical margins in oral cancer patients with respect to various types of reconstruction South Asian Journal of Cancer free flap margins oral cancers primary closure reconstruction |
| title | Adequacy of surgical margins in oral cancer patients with respect to various types of reconstruction |
| title_full | Adequacy of surgical margins in oral cancer patients with respect to various types of reconstruction |
| title_fullStr | Adequacy of surgical margins in oral cancer patients with respect to various types of reconstruction |
| title_full_unstemmed | Adequacy of surgical margins in oral cancer patients with respect to various types of reconstruction |
| title_short | Adequacy of surgical margins in oral cancer patients with respect to various types of reconstruction |
| title_sort | adequacy of surgical margins in oral cancer patients with respect to various types of reconstruction |
| topic | free flap margins oral cancers primary closure reconstruction |
| url | http://www.thieme-connect.de/DOI/DOI?10.4103/sajc.sajc_366_18 |
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