Solasonine Inhibits Pancreatic Cancer Progression With Involvement of Ferroptosis Induction

Solasonine Inhibits Pancreatic Cancer Progression With Involvement of Ferroptosis Induction

Pancreatic cancer is a highly fatal malignant tumor of the digestive system. It is characterized by early metastasis and high mortality rates. Solasonine, a steroidal alkaloid, is derived from Solanum nigrum L., a natural herb. Solasonine is associated with excellent anti-tumor effects, however, its...

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Bibliographic Details
Main Authors: Xiaoqiang Liang, Cheng Hu, Mian Han, Congying Liu, Xun Sun, Kui Yu, Honggang Gu, Jingzhe Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Oncology
Subjects:
solasonine
pancreatic cancer
ferroptosis
SLC7A11
OTUB1
TFAP2A
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.834729/full

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