RIPK3 promotes brain region-specific interferon signaling and restriction of tick-borne flavivirus infection.

RIPK3 promotes brain region-specific interferon signaling and restriction of tick-borne flavivirus infection.

Innate immune signaling in the central nervous system (CNS) exhibits many remarkable specializations that vary across cell types and CNS regions. In the setting of neuroinvasive flavivirus infection, neurons employ the immunologic kinase receptor-interacting kinase 3 (RIPK3) to promote an antiviral...

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Bibliographic Details
Main Authors: Marissa Lindman, Juan P Angel, Irving Estevez, Nydia P Chang, Tsui-Wen Chou, Micheal McCourt, Colm Atkins, Brian P Daniels
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-11-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011813&type=printable

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https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1011813&type=printable

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