Antihypoxic Activity of 2,5-diaryl-8,8-dimethyl-3,6,7,8-tetrahydro-2<i>H</i>-pyrido[4,3,2-<i>de</i>]quinnolin-3-ones

Antihypoxic Activity of 2,5-diaryl-8,8-dimethyl-3,6,7,8-tetrahydro-2<i>H</i>-pyrido[4,3,2-<i>de</i>]quinnolin-3-ones

Introduction. The state of hypoxia, causing damage and cell death, underlies many pathological processes. In addition, hypoxia induces a state of free radical oxidation, which enhances the damaging effect of hypoxic damage. This necessitates the synthesis of new compounds and the creation on their b...

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Bibliographic Details
Main Authors: S. S. Zykova, K. V. Namyatova, K. L. Gankova, E. A. Lystsova, T. V. Shavrina, S. N. Shurov
Format: Article
Language:Russian
Published: LLC Center of Pharmaceutical Analytics (LLC «CPHA») 2022-12-01
Series:Разработка и регистрация лекарственных средств
Subjects:
2,5-диарил-8,8-диметил-3,6,7,8-тетрагидро-2<i>н</i>-пиридо[4,3,2-<i>de</i>]хиннолин-3-оны
антигипоксическая активность
трициклические гетероциклы
нормобарическая гипоксия
гиперкапния
Online Access:https://www.pharmjournal.ru/jour/article/view/1389

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