BODIPY-based fluorescent liposomes with sesquiterpene lactone trilobolide

BODIPY-based fluorescent liposomes with sesquiterpene lactone trilobolide

Like thapsigargin, which is undergoing clinical trials, trilobolide is a natural product with promising anticancer and anti-inflammatory properties. Similar to thapsigargin, it has limited aqueous solubility that strongly reduces its potential medicinal applications. The targeted delivery of hydroph...

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Bibliographic Details
Main Authors: Ludmila Škorpilová, Silvie Rimpelová, Michal Jurášek, Miloš Buděšínský, Jana Lokajová, Roman Effenberg, Petr Slepička, Tomáš Ruml, Eva Kmoníčková, Pavel B. Drašar, Zdeněk Wimmer
Format: Article
Language:English
Published: Beilstein-Institut 2017-07-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
BODIPY conjugates
cancer targeting
drug delivery
liposomes
natural compounds
sesquiterpene lactone trilobolide
Online Access:https://doi.org/10.3762/bjoc.13.128

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