Evaluation of the effects of magnesium supplement in primary and secondary preventions of nephrolithiasis: a systematic review
Introduction: The role of magnesium supplement to prevent primary and/or secondary kidney stones has not been fully determined. The aim of this study is to evaluate the effects of magnesium supplement in modifying urinary risk factors of recurrent kidney stones.Method: We searched MEDLINE, Scopus, a...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2016-01-01
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| Series: | Reviews in Clinical Medicine |
| Subjects: | |
| Online Access: | https://rcm.mums.ac.ir/article_6027_28b4c4f598f42fce86cc73f0dc237a6e.pdf |
| _version_ | 1797976086706913280 |
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| author | Anoush Azarfar Mohammad Esmaeili Nayere Tousi Mitra Naseri Fatemeh Ghane Yalda Ravanshad Anahita Alizadeh |
| author_facet | Anoush Azarfar Mohammad Esmaeili Nayere Tousi Mitra Naseri Fatemeh Ghane Yalda Ravanshad Anahita Alizadeh |
| author_sort | Anoush Azarfar |
| collection | DOAJ |
| description | Introduction: The role of magnesium supplement to prevent primary and/or secondary kidney stones has not been fully determined. The aim of this study is to evaluate the effects of magnesium supplement in modifying urinary risk factors of recurrent kidney stones.Method: We searched MEDLINE, Scopus, and Google Scholar databases on December 7, 2014 and reference lists of systematic reviews and randomized, controlled trials. Among the initial 282 articles found by our search strategy and hand searching, we found eight English-language studies were eligible for our study.Result: Magnesium supplementation could be beneficial in nephrolithiasis prevention through increasing urinary magnesium, citrate, and calcium while declining urinary oxalate. In pediatric patients, the results were more prominent and could decline urinary oxalate up to 90% of the baseline.Conclusions: Magnesium supplementation could be beneficial, especially with potassium-citrate combination. However, due to the low number of well-designed randomized controlled trials, especially in pediatrics, the conclusions of this study need further confirmation. |
| first_indexed | 2024-04-11T04:45:47Z |
| format | Article |
| id | doaj.art-95b9d31d44db475ab899ccacb0d38e07 |
| institution | Directory Open Access Journal |
| issn | 2345-6256 2345-6892 |
| language | English |
| last_indexed | 2024-04-11T04:45:47Z |
| publishDate | 2016-01-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Reviews in Clinical Medicine |
| spelling | doaj.art-95b9d31d44db475ab899ccacb0d38e072022-12-27T13:10:46ZengMashhad University of Medical SciencesReviews in Clinical Medicine2345-62562345-68922016-01-0131182210.17463/RCM.2016.01.0056027Evaluation of the effects of magnesium supplement in primary and secondary preventions of nephrolithiasis: a systematic reviewAnoush Azarfar0Mohammad Esmaeili1Nayere Tousi2Mitra Naseri3Fatemeh Ghane4Yalda Ravanshad5Anahita Alizadeh6Department of Pediatric, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Department of Pediatric, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Student Research Committee, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Department of Pediatric, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Department of Pediatric, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Clinical Research Development Unit, Ghaem Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.Department of Clinical Toxicology, Imam Reza Hospital, School of Medicine, Mashhad University of Medical Science, Mashhad, Iran.Introduction: The role of magnesium supplement to prevent primary and/or secondary kidney stones has not been fully determined. The aim of this study is to evaluate the effects of magnesium supplement in modifying urinary risk factors of recurrent kidney stones.Method: We searched MEDLINE, Scopus, and Google Scholar databases on December 7, 2014 and reference lists of systematic reviews and randomized, controlled trials. Among the initial 282 articles found by our search strategy and hand searching, we found eight English-language studies were eligible for our study.Result: Magnesium supplementation could be beneficial in nephrolithiasis prevention through increasing urinary magnesium, citrate, and calcium while declining urinary oxalate. In pediatric patients, the results were more prominent and could decline urinary oxalate up to 90% of the baseline.Conclusions: Magnesium supplementation could be beneficial, especially with potassium-citrate combination. However, due to the low number of well-designed randomized controlled trials, especially in pediatrics, the conclusions of this study need further confirmation.https://rcm.mums.ac.ir/article_6027_28b4c4f598f42fce86cc73f0dc237a6e.pdfmagnesiumnephrolithiasispreventionsupplementation |
| spellingShingle | Anoush Azarfar Mohammad Esmaeili Nayere Tousi Mitra Naseri Fatemeh Ghane Yalda Ravanshad Anahita Alizadeh Evaluation of the effects of magnesium supplement in primary and secondary preventions of nephrolithiasis: a systematic review Reviews in Clinical Medicine magnesium nephrolithiasis prevention supplementation |
| title | Evaluation of the effects of magnesium supplement in primary and secondary preventions of nephrolithiasis: a systematic review |
| title_full | Evaluation of the effects of magnesium supplement in primary and secondary preventions of nephrolithiasis: a systematic review |
| title_fullStr | Evaluation of the effects of magnesium supplement in primary and secondary preventions of nephrolithiasis: a systematic review |
| title_full_unstemmed | Evaluation of the effects of magnesium supplement in primary and secondary preventions of nephrolithiasis: a systematic review |
| title_short | Evaluation of the effects of magnesium supplement in primary and secondary preventions of nephrolithiasis: a systematic review |
| title_sort | evaluation of the effects of magnesium supplement in primary and secondary preventions of nephrolithiasis a systematic review |
| topic | magnesium nephrolithiasis prevention supplementation |
| url | https://rcm.mums.ac.ir/article_6027_28b4c4f598f42fce86cc73f0dc237a6e.pdf |
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