Brief Report: Droplet Digital Polymerase Chain Reaction Versus Plasma Next-Generation Sequencing in Detecting Clearance of Plasma EGFR Mutations and Carcinoembryonic Antigen Levels as a Surrogate Measure

Brief Report: Droplet Digital Polymerase Chain Reaction Versus Plasma Next-Generation Sequencing in Detecting Clearance of Plasma EGFR Mutations and Carcinoembryonic Antigen Levels as a Surrogate Measure

Introduction: To compare the performance of droplet digital polymerase chain reaction (ddPCR) and plasma next-generation sequencing (NGS) in detecting clearance of plasma EGFR (pEGFR) mutations. Methods: Patients with treatment-naive advanced EGFR-mutated lung cancer treated with first-line tyrosine...

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Bibliographic Details
Main Authors: Stephanie P.L. Saw, MRCP, Gek San Tan, MSc, Wei Chong Tan, MRCP, Aaron C. Tan, PhD, Gillianne G.Y. Lai, MRCP, Darren W.T. Lim, MRCP, Ravindran Kanesvaran, MRCP, Wan Ling Tan, MRCP, Sze Huey Tan, PhD, Kiat Hon Lim, FRCPA, Anders J. Skanderup, PhD, Daniel S.W. Tan, PhD
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:JTO Clinical and Research Reports
Subjects:
EGFR-mutated NSCLC
ddPCR
NGS
CEA
Online Access:http://www.sciencedirect.com/science/article/pii/S266636432300142X

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