Comparing the effect of phytobiotic, coccidiostat, toltrazuril, and vaccine on the prevention and treatment of coccidiosis in broilers
ABSTRACT: This study compared 2 herbal anticoccidiosis drugs (water-soluble and feed-additive drugs) with monensin coccidiostat, toltrazuril (TTZ, anticoccidiosis drug), and Livacox Q (anticoccidiosis vaccine) in terms of their effects on the prevention and treatment of coccidiosis in broilers. In t...
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| Format: | Article |
| Language: | English |
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Elsevier
2024-05-01
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| Series: | Poultry Science |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S0032579124001755 |
| _version_ | 1797263679949897728 |
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| author | Hesam Shahininejad Shaban Rahimi Mohammad Amir Karimi Torshizi Fatemeh Arabkhazaeli Mahdi Ayyari Alireza Behnamifar Morteza Abuali Jesse Grimes |
| author_facet | Hesam Shahininejad Shaban Rahimi Mohammad Amir Karimi Torshizi Fatemeh Arabkhazaeli Mahdi Ayyari Alireza Behnamifar Morteza Abuali Jesse Grimes |
| author_sort | Hesam Shahininejad |
| collection | DOAJ |
| description | ABSTRACT: This study compared 2 herbal anticoccidiosis drugs (water-soluble and feed-additive drugs) with monensin coccidiostat, toltrazuril (TTZ, anticoccidiosis drug), and Livacox Q (anticoccidiosis vaccine) in terms of their effects on the prevention and treatment of coccidiosis in broilers. In this study, 280 Ross 308 broiler chickens (a mix of both genders) were used in a completely randomized design with 7 treatments and 5 replications each including 8 chickens per replicate. On d 21 of rearing, all experimental groups, except for the negative control group (NC), were challenged with a mixed suspension of common strains of Eimeria, and the intended indices were assessed, including performance indices, number of oocysts per gram (OPG) of feces, intestinal injuries, and the total number of intestinal bacteria. In addition, the NC and the group receiving the monensin had greater body weight gain (BWG) (P < 0.05). At the end of week 6, the monensin group had the highest feed intake (FI), while the water soluble medicine treatment resulted in the lowest feed intake (P < 0.05). Regarding the lesion scores on day 28, the highest and lowest rates of jejunal injuries were observed in the positive control group (PC), the monensin and vaccine group respectively. The rate of oocysts excretion (oocysts per gram of feces = OPG) on different days was higher in the PC group, and the use of monensin could further reduce excretion compared to the other groups (P > 0.05). Based on a comparison of the population of lactic acid bacteria between the NC and both medicinal plant treated groups, the use of these products could increase the population of these types of bacteria. Moreover, the population of Escherichia coli was less considerable in the NC and herbal powder groups (P < 0.05). Overall, similar to commercial medicines, the herbal medicines used in this project can be effective in the prevention and treatment of coccidiosis and can improve profitability in broiler rearing centers by improving intestinal health. |
| first_indexed | 2024-04-25T00:16:51Z |
| format | Article |
| id | doaj.art-95bb137173e24ef9a2888ceb71c33375 |
| institution | Directory Open Access Journal |
| issn | 0032-5791 |
| language | English |
| last_indexed | 2024-04-25T00:16:51Z |
| publishDate | 2024-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Poultry Science |
| spelling | doaj.art-95bb137173e24ef9a2888ceb71c333752024-03-13T04:44:50ZengElsevierPoultry Science0032-57912024-05-011035103596Comparing the effect of phytobiotic, coccidiostat, toltrazuril, and vaccine on the prevention and treatment of coccidiosis in broilersHesam Shahininejad0Shaban Rahimi1Mohammad Amir Karimi Torshizi2Fatemeh Arabkhazaeli3Mahdi Ayyari4Alireza Behnamifar5Morteza Abuali6Jesse Grimes7Department of Poultry Science, Faculty of Agriculture, Tarbiat Modares University, Tehran, 14117-13116 IranDepartment of Poultry Science, Faculty of Agriculture, Tarbiat Modares University, Tehran, 14117-13116 IranDepartment of Poultry Science, Faculty of Agriculture, Tarbiat Modares University, Tehran, 14117-13116 IranDepartment of Parasitology, Faculty of Veterinary Medicine, University of Tehran, 14199-63114 IranDepartment of Horticultural Science, Faculty of Agriculture, Tarbiat Modares University, Tehran, 14117-13116 IranDepartment of Poultry Science, Faculty of Agriculture, Tarbiat Modares University, Tehran, 14117-13116 IranDepartment of Pharmacognosy, Institute of Medicinal Plants-ACECR, Karaj, Alborz, 1419815477 IranPrestage Department of Poultry Science, College of Agriculture and Life Sciences, North Carolina State University, Raleigh, NC 27695-7608 USA; Corresponding author:ABSTRACT: This study compared 2 herbal anticoccidiosis drugs (water-soluble and feed-additive drugs) with monensin coccidiostat, toltrazuril (TTZ, anticoccidiosis drug), and Livacox Q (anticoccidiosis vaccine) in terms of their effects on the prevention and treatment of coccidiosis in broilers. In this study, 280 Ross 308 broiler chickens (a mix of both genders) were used in a completely randomized design with 7 treatments and 5 replications each including 8 chickens per replicate. On d 21 of rearing, all experimental groups, except for the negative control group (NC), were challenged with a mixed suspension of common strains of Eimeria, and the intended indices were assessed, including performance indices, number of oocysts per gram (OPG) of feces, intestinal injuries, and the total number of intestinal bacteria. In addition, the NC and the group receiving the monensin had greater body weight gain (BWG) (P < 0.05). At the end of week 6, the monensin group had the highest feed intake (FI), while the water soluble medicine treatment resulted in the lowest feed intake (P < 0.05). Regarding the lesion scores on day 28, the highest and lowest rates of jejunal injuries were observed in the positive control group (PC), the monensin and vaccine group respectively. The rate of oocysts excretion (oocysts per gram of feces = OPG) on different days was higher in the PC group, and the use of monensin could further reduce excretion compared to the other groups (P > 0.05). Based on a comparison of the population of lactic acid bacteria between the NC and both medicinal plant treated groups, the use of these products could increase the population of these types of bacteria. Moreover, the population of Escherichia coli was less considerable in the NC and herbal powder groups (P < 0.05). Overall, similar to commercial medicines, the herbal medicines used in this project can be effective in the prevention and treatment of coccidiosis and can improve profitability in broiler rearing centers by improving intestinal health.http://www.sciencedirect.com/science/article/pii/S0032579124001755coccidiosisvaccinemonensinlesion scoresoocyst excretion |
| spellingShingle | Hesam Shahininejad Shaban Rahimi Mohammad Amir Karimi Torshizi Fatemeh Arabkhazaeli Mahdi Ayyari Alireza Behnamifar Morteza Abuali Jesse Grimes Comparing the effect of phytobiotic, coccidiostat, toltrazuril, and vaccine on the prevention and treatment of coccidiosis in broilers Poultry Science coccidiosis vaccine monensin lesion scores oocyst excretion |
| title | Comparing the effect of phytobiotic, coccidiostat, toltrazuril, and vaccine on the prevention and treatment of coccidiosis in broilers |
| title_full | Comparing the effect of phytobiotic, coccidiostat, toltrazuril, and vaccine on the prevention and treatment of coccidiosis in broilers |
| title_fullStr | Comparing the effect of phytobiotic, coccidiostat, toltrazuril, and vaccine on the prevention and treatment of coccidiosis in broilers |
| title_full_unstemmed | Comparing the effect of phytobiotic, coccidiostat, toltrazuril, and vaccine on the prevention and treatment of coccidiosis in broilers |
| title_short | Comparing the effect of phytobiotic, coccidiostat, toltrazuril, and vaccine on the prevention and treatment of coccidiosis in broilers |
| title_sort | comparing the effect of phytobiotic coccidiostat toltrazuril and vaccine on the prevention and treatment of coccidiosis in broilers |
| topic | coccidiosis vaccine monensin lesion scores oocyst excretion |
| url | http://www.sciencedirect.com/science/article/pii/S0032579124001755 |
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