Common and Distinct Disruptions of Cortical Surface Morphology Between Autism Spectrum Disorder Children With and Without SHANK3 Deficiency

Common and Distinct Disruptions of Cortical Surface Morphology Between Autism Spectrum Disorder Children With and Without SHANK3 Deficiency

SH3 and Multiple Ankyrin Repeat Domains 3 (SHANK3)-caused autism spectrum disorder (ASD) may present a unique opportunity to clarify the heterogeneous neuropathological mechanisms of ASD. However, the specificity and commonality of disrupted large-scale brain organization in SHANK3-deficient childre...

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Bibliographic Details
Main Authors: Dongyun Li, Chunxue Liu, Ziyi Huang, Huiping Li, Qiong Xu, Bingrui Zhou, Chunchun Hu, Ying Zhang, Yi Wang, Jingxin Nie, Zhongwei Qiao, Dazhi Yin, Xiu Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Neuroscience
Subjects:
surface-based morphometry
structural covariance networks
autism spectrum disorder
SHANK3
children
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2021.751364/full

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