Resveratrol Attenuates the Mitochondrial RNA-Mediated Cellular Response to Immunogenic Stress

Resveratrol Attenuates the Mitochondrial RNA-Mediated Cellular Response to Immunogenic Stress

Human mitochondria contain a circular genome that encodes 13 subunits of the oxidative phosphorylation system. In addition to their role as powerhouses of the cells, mitochondria are also involved in innate immunity as the mitochondrial genome generates long double-stranded RNAs (dsRNAs) that can ac...

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Bibliographic Details
Main Authors: Jimin Yoon, Doyeong Ku, Minseok Lee, Namseok Lee, Sung Gap Im, Yoosik Kim
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:International Journal of Molecular Sciences
Subjects:
resveratrol
Sjögren’s syndrome
innate immunity
immunogenic stress
dsRNA stress
oligomycin A
Online Access:https://www.mdpi.com/1422-0067/24/8/7403

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