Cardiovascular Disorder after Cardiotoxic Non-Hodking’s Lymphoma Treatment: A Case Report

The non-Hodgkin’s lymphomas are a diverse group of lymphoid neoplasms that collectively rank fifth in cancer incidence and mortality. Patients treated with mediastinal radiotherapy and/or anthracycline-containing chemotherapy are known to have increased risks of coronary heart disease, valvular hear...

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Main Authors: Diana Žaliaduonytė, Rita Kleinauskienė, Gintarė Muckienė, Vytautas Zabiela
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Medicina
Subjects:
Online Access:https://www.mdpi.com/1648-9144/58/4/489
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author Diana Žaliaduonytė
Rita Kleinauskienė
Gintarė Muckienė
Vytautas Zabiela
author_facet Diana Žaliaduonytė
Rita Kleinauskienė
Gintarė Muckienė
Vytautas Zabiela
author_sort Diana Žaliaduonytė
collection DOAJ
description The non-Hodgkin’s lymphomas are a diverse group of lymphoid neoplasms that collectively rank fifth in cancer incidence and mortality. Patients treated with mediastinal radiotherapy and/or anthracycline-containing chemotherapy are known to have increased risks of coronary heart disease, valvular heart disease, and heart failure. This may be the result of cancer treatment cardiotoxicity or may be due to accelerated development of cardiovascular disease. We presented 41-year-old male who was admitted to the hospital because of congestive heart failure. He has a medical history of non-Hodgkin’s lymphoma treated with anthracycline-based chemotherapy and mediastinal radiotherapy almost 20 years ago. Echocardiography showed significant aortic valve stenosis, thickened and fibrotic pericardium. Coronary angiography showed diffuse three-vessel coronary artery disease. The patient was referred for surgical treatment. Aortic valve replacement, coronary artery bypass grafting and pericardiectomy were successfully performed, symptoms of heart failure reduced.
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spelling doaj.art-95cc17b3a0154c9c91fd237608a2a5f92023-11-30T21:30:15ZengMDPI AGMedicina1010-660X1648-91442022-03-0158448910.3390/medicina58040489Cardiovascular Disorder after Cardiotoxic Non-Hodking’s Lymphoma Treatment: A Case ReportDiana Žaliaduonytė0Rita Kleinauskienė1Gintarė Muckienė2Vytautas Zabiela3Department of Cardiology, Medical Academy, Hospital of Lithuanian University of Health Sciences, Eivenių St. 2, 50161 Kaunas, LithuaniaDepartment of Cardiology, Medical Academy, Hospital of Lithuanian University of Health Sciences, Eivenių St. 2, 50161 Kaunas, LithuaniaDepartment of Cardiology, Medical Academy, Hospital of Lithuanian University of Health Sciences, Eivenių St. 2, 50161 Kaunas, LithuaniaDepartment of Cardiology, Medical Academy, Hospital of Lithuanian University of Health Sciences, Eivenių St. 2, 50161 Kaunas, LithuaniaThe non-Hodgkin’s lymphomas are a diverse group of lymphoid neoplasms that collectively rank fifth in cancer incidence and mortality. Patients treated with mediastinal radiotherapy and/or anthracycline-containing chemotherapy are known to have increased risks of coronary heart disease, valvular heart disease, and heart failure. This may be the result of cancer treatment cardiotoxicity or may be due to accelerated development of cardiovascular disease. We presented 41-year-old male who was admitted to the hospital because of congestive heart failure. He has a medical history of non-Hodgkin’s lymphoma treated with anthracycline-based chemotherapy and mediastinal radiotherapy almost 20 years ago. Echocardiography showed significant aortic valve stenosis, thickened and fibrotic pericardium. Coronary angiography showed diffuse three-vessel coronary artery disease. The patient was referred for surgical treatment. Aortic valve replacement, coronary artery bypass grafting and pericardiectomy were successfully performed, symptoms of heart failure reduced.https://www.mdpi.com/1648-9144/58/4/489aortic valve stenosiscoronary artery diseaseheart failurecardiotoxic treatment
spellingShingle Diana Žaliaduonytė
Rita Kleinauskienė
Gintarė Muckienė
Vytautas Zabiela
Cardiovascular Disorder after Cardiotoxic Non-Hodking’s Lymphoma Treatment: A Case Report
Medicina
aortic valve stenosis
coronary artery disease
heart failure
cardiotoxic treatment
title Cardiovascular Disorder after Cardiotoxic Non-Hodking’s Lymphoma Treatment: A Case Report
title_full Cardiovascular Disorder after Cardiotoxic Non-Hodking’s Lymphoma Treatment: A Case Report
title_fullStr Cardiovascular Disorder after Cardiotoxic Non-Hodking’s Lymphoma Treatment: A Case Report
title_full_unstemmed Cardiovascular Disorder after Cardiotoxic Non-Hodking’s Lymphoma Treatment: A Case Report
title_short Cardiovascular Disorder after Cardiotoxic Non-Hodking’s Lymphoma Treatment: A Case Report
title_sort cardiovascular disorder after cardiotoxic non hodking s lymphoma treatment a case report
topic aortic valve stenosis
coronary artery disease
heart failure
cardiotoxic treatment
url https://www.mdpi.com/1648-9144/58/4/489
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AT ritakleinauskiene cardiovasculardisorderaftercardiotoxicnonhodkingslymphomatreatmentacasereport
AT gintaremuckiene cardiovasculardisorderaftercardiotoxicnonhodkingslymphomatreatmentacasereport
AT vytautaszabiela cardiovasculardisorderaftercardiotoxicnonhodkingslymphomatreatmentacasereport