New Indications for Liver Transplantation

Liver transplantation (LT) is an important therapeutic option for the treatment of several liver diseases. Modern LT is characterized by remarkable improvements in post-transplant patient survival, graft survival, and quality of life. Thanks to these great improvements, indications for LT are expand...

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Main Authors: Alberto Zanetto, Sarah Shalaby, Martina Gambato, Giacomo Germani, Marco Senzolo, Debora Bizzaro, Francesco Paolo Russo, Patrizia Burra
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/10/17/3867
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author Alberto Zanetto
Sarah Shalaby
Martina Gambato
Giacomo Germani
Marco Senzolo
Debora Bizzaro
Francesco Paolo Russo
Patrizia Burra
author_facet Alberto Zanetto
Sarah Shalaby
Martina Gambato
Giacomo Germani
Marco Senzolo
Debora Bizzaro
Francesco Paolo Russo
Patrizia Burra
author_sort Alberto Zanetto
collection DOAJ
description Liver transplantation (LT) is an important therapeutic option for the treatment of several liver diseases. Modern LT is characterized by remarkable improvements in post-transplant patient survival, graft survival, and quality of life. Thanks to these great improvements, indications for LT are expanding. Nowadays, clinical conditions historically considered exclusion criteria for LT, have been considered new indications for LT, showing survival advantages for patients. In this review, we provide an updated overview of the principal newer indications for LT, with particular attention to alcoholic hepatitis, acute-on-chronic liver failure (ACLF), cholangiocarcinoma and colorectal cancer metastases.
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spelling doaj.art-95d00b73c64d46b48efd9f0c0c96a34e2023-11-22T10:48:35ZengMDPI AGJournal of Clinical Medicine2077-03832021-08-011017386710.3390/jcm10173867New Indications for Liver TransplantationAlberto Zanetto0Sarah Shalaby1Martina Gambato2Giacomo Germani3Marco Senzolo4Debora Bizzaro5Francesco Paolo Russo6Patrizia Burra7Multivisceral Transplant Unit, Department of Surgery Oncology and Gastroenterology, University of Padova, Via Giustiniani 2, 35128 Padova, ItalyMultivisceral Transplant Unit, Department of Surgery Oncology and Gastroenterology, University of Padova, Via Giustiniani 2, 35128 Padova, ItalyMultivisceral Transplant Unit, Department of Surgery Oncology and Gastroenterology, University of Padova, Via Giustiniani 2, 35128 Padova, ItalyMultivisceral Transplant Unit, Department of Surgery Oncology and Gastroenterology, University of Padova, Via Giustiniani 2, 35128 Padova, ItalyMultivisceral Transplant Unit, Department of Surgery Oncology and Gastroenterology, University of Padova, Via Giustiniani 2, 35128 Padova, ItalyMultivisceral Transplant Unit, Department of Surgery Oncology and Gastroenterology, University of Padova, Via Giustiniani 2, 35128 Padova, ItalyMultivisceral Transplant Unit, Department of Surgery Oncology and Gastroenterology, University of Padova, Via Giustiniani 2, 35128 Padova, ItalyMultivisceral Transplant Unit, Department of Surgery Oncology and Gastroenterology, University of Padova, Via Giustiniani 2, 35128 Padova, ItalyLiver transplantation (LT) is an important therapeutic option for the treatment of several liver diseases. Modern LT is characterized by remarkable improvements in post-transplant patient survival, graft survival, and quality of life. Thanks to these great improvements, indications for LT are expanding. Nowadays, clinical conditions historically considered exclusion criteria for LT, have been considered new indications for LT, showing survival advantages for patients. In this review, we provide an updated overview of the principal newer indications for LT, with particular attention to alcoholic hepatitis, acute-on-chronic liver failure (ACLF), cholangiocarcinoma and colorectal cancer metastases.https://www.mdpi.com/2077-0383/10/17/3867alcoholic hepatitisacute-on-chronic liver failurecholangiocarcinomacolorectal cancer metastases
spellingShingle Alberto Zanetto
Sarah Shalaby
Martina Gambato
Giacomo Germani
Marco Senzolo
Debora Bizzaro
Francesco Paolo Russo
Patrizia Burra
New Indications for Liver Transplantation
Journal of Clinical Medicine
alcoholic hepatitis
acute-on-chronic liver failure
cholangiocarcinoma
colorectal cancer metastases
title New Indications for Liver Transplantation
title_full New Indications for Liver Transplantation
title_fullStr New Indications for Liver Transplantation
title_full_unstemmed New Indications for Liver Transplantation
title_short New Indications for Liver Transplantation
title_sort new indications for liver transplantation
topic alcoholic hepatitis
acute-on-chronic liver failure
cholangiocarcinoma
colorectal cancer metastases
url https://www.mdpi.com/2077-0383/10/17/3867
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AT martinagambato newindicationsforlivertransplantation
AT giacomogermani newindicationsforlivertransplantation
AT marcosenzolo newindicationsforlivertransplantation
AT deborabizzaro newindicationsforlivertransplantation
AT francescopaolorusso newindicationsforlivertransplantation
AT patriziaburra newindicationsforlivertransplantation