Anti-biofilm activity of caffeine against uropathogenic E. coli is mediated by curli biogenesis

Abstract Biofilms are assemblages of sessile microorganisms that form an extracellular matrix around themselves and mediate attachment to surfaces. The major component of the extracellular matrix of Uropathogenic E. coli and other Enterobacteriaceae are curli fibers, making biofilms robust and resis...

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Bibliographic Details
Main Authors: Bhawna Rathi, Surbhi Gupta, Parveen Kumar, Veerbhan Kesarwani, Rakesh Singh Dhanda, Sandeep Kumar Kushwaha, Manisha Yadav
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-022-23647-2