Evaluation of Pharmacogenetics of Drug-Metabolizing Enzymes and Drug Efflux Transporter in Renal Transplants Receiving Immunosuppressants

Evaluation of Pharmacogenetics of Drug-Metabolizing Enzymes and Drug Efflux Transporter in Renal Transplants Receiving Immunosuppressants

Cytochrome P450 (CYP) enzymes, such as <i>CYP3A4,</i> and <i>CYP3A5</i>, P450 oxidoreductase (POR), peroxisome proliferator activated receptor alpha (PPAR-alpha), and drug transporter (ABCB1) were observed to influence concentrations of immunosuppressants (cyclosporine, evero...

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Bibliographic Details
Main Authors: Kannan Sridharan, Shamik Shah, Anfal Jassim, Mona Hammad, Johaina Ebrahim Al Gadhban, Ola Al Segai
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Journal of Personalized Medicine
Subjects:
sirolimus
tacrolimus
cyclosporine
Online Access:https://www.mdpi.com/2075-4426/12/5/823

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