Effect of probiotics on giardiasis. Where are we?

ABSTRACT Giardiasis, an intestinal infection caused by Giardia lamblia, was recently included in the ‘Neglected Diseases Initiative’ by the World Health Organization. Symptomatic patients can develop mild diarrhea up to a severe malabsorption syndrome, and children may show significantly impaired co...

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Main Authors: Luciana Laranjo Amorim Ventura, Dirce Ribeiro de Oliveira, Maria Aparecida Gomes, Marcia Regina Fantoni Torres
Format: Article
Language:English
Published: Universidade de São Paulo 2018-07-01
Series:Brazilian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000200401&lng=en&tlng=en
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author Luciana Laranjo Amorim Ventura
Dirce Ribeiro de Oliveira
Maria Aparecida Gomes
Marcia Regina Fantoni Torres
author_facet Luciana Laranjo Amorim Ventura
Dirce Ribeiro de Oliveira
Maria Aparecida Gomes
Marcia Regina Fantoni Torres
author_sort Luciana Laranjo Amorim Ventura
collection DOAJ
description ABSTRACT Giardiasis, an intestinal infection caused by Giardia lamblia, was recently included in the ‘Neglected Diseases Initiative’ by the World Health Organization. Symptomatic patients can develop mild diarrhea up to a severe malabsorption syndrome, and children may show significantly impaired cognitive and physical development. Currently, nitroimidazoles are the main class of antibiotic used to treat giardiasis. Despite the efficacy of these drugs, adverse effects and reported resistance have increased, encouraging studies to identify and develop therapeutic alternatives. In this context, probiotics may represent an attractive option. Probiotics are defined as live microorganisms that, when administered in suitable amounts, confer a health benefit to the host. The use of probiotics in the treatment of parasitosis has been suggested because of its beneficial effects, such as a reduced time of gastrointestinal symptoms and parasite load in animal models and humans. Probiotics have been studied as an alternative treatment for giardiasis. In this review, we evaluated probiotic effectiveness in the treatment and prevention of this disease. Based on the studies examined herein, we conclude that probiotics have a beneficial effect on the modulation of giardiasis.
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spelling doaj.art-95dc7c4ab19a4a62a6ce1453eff999c02022-12-21T21:21:41ZengUniversidade de São PauloBrazilian Journal of Pharmaceutical Sciences2175-97902018-07-0154210.1590/s2175-97902018000217360S1984-82502018000200401Effect of probiotics on giardiasis. Where are we?Luciana Laranjo Amorim VenturaDirce Ribeiro de OliveiraMaria Aparecida GomesMarcia Regina Fantoni TorresABSTRACT Giardiasis, an intestinal infection caused by Giardia lamblia, was recently included in the ‘Neglected Diseases Initiative’ by the World Health Organization. Symptomatic patients can develop mild diarrhea up to a severe malabsorption syndrome, and children may show significantly impaired cognitive and physical development. Currently, nitroimidazoles are the main class of antibiotic used to treat giardiasis. Despite the efficacy of these drugs, adverse effects and reported resistance have increased, encouraging studies to identify and develop therapeutic alternatives. In this context, probiotics may represent an attractive option. Probiotics are defined as live microorganisms that, when administered in suitable amounts, confer a health benefit to the host. The use of probiotics in the treatment of parasitosis has been suggested because of its beneficial effects, such as a reduced time of gastrointestinal symptoms and parasite load in animal models and humans. Probiotics have been studied as an alternative treatment for giardiasis. In this review, we evaluated probiotic effectiveness in the treatment and prevention of this disease. Based on the studies examined herein, we conclude that probiotics have a beneficial effect on the modulation of giardiasis.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000200401&lng=en&tlng=enGiardia lambliaGiardiasisProbiotics/effects/evaluation
spellingShingle Luciana Laranjo Amorim Ventura
Dirce Ribeiro de Oliveira
Maria Aparecida Gomes
Marcia Regina Fantoni Torres
Effect of probiotics on giardiasis. Where are we?
Brazilian Journal of Pharmaceutical Sciences
Giardia lamblia
Giardiasis
Probiotics/effects/evaluation
title Effect of probiotics on giardiasis. Where are we?
title_full Effect of probiotics on giardiasis. Where are we?
title_fullStr Effect of probiotics on giardiasis. Where are we?
title_full_unstemmed Effect of probiotics on giardiasis. Where are we?
title_short Effect of probiotics on giardiasis. Where are we?
title_sort effect of probiotics on giardiasis where are we
topic Giardia lamblia
Giardiasis
Probiotics/effects/evaluation
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502018000200401&lng=en&tlng=en
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