Exogenetic over-expression of pBDNF affects learning and memory in APPswePS1dE9 transgenic mice

Exogenetic over-expression of pBDNF affects learning and memory in APPswePS1dE9 transgenic mice

Objective To explore the effect and possible machanism of recombinant adeno-associated virus (rAAV) vector containing brain-derived neurotrophic factor propeptide (AAV-pBDNF) on learning and memory in APPswePS1dE9 transgenic mice (Alzheimer's disease, AD). Methods A total of 18 APPswePS1dE9 tra...

Full description

Bibliographic Details
Main Authors: XU Manyu, ZAHNG Yuan, YI Xu, XU Zhiqiang
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2021-04-01
Series:Di-san junyi daxue xuebao
Subjects:
brain-derived neurotrophic factor propeptide
alzheimer's disease
learning and memory
postsynaptic density protein 95
Online Access:https://aammt.tmmu.edu.cn/Upload/rhtml/202011150.htm

Internet

https://aammt.tmmu.edu.cn/Upload/rhtml/202011150.htm

Similar Items