SETDB1 promotes progression through upregulation of SF3B4 expression and regulates the immunity in ovarian cancer

SETDB1 promotes progression through upregulation of SF3B4 expression and regulates the immunity in ovarian cancer

Abstract Background Ovarian cancer (OC) is the most lethal gynecologic malignant tumour. The mechanism promoting OC initiation and progression remains unclear. SET domain bifurcated histone lysine methyltransferase 1(SETDB1) acts as an oncogene in a variety of tumours. This study aims to explore the...

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Bibliographic Details
Main Authors: Hongjuan Yang, Lei Sui, Cuicui Cai, Huijun Chu, Yuchao Diao
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Journal of Ovarian Research
Subjects:
SETDB1
Transcription factor
SF3B4
Ovarian cancer
Tumour immunity
Online Access:https://doi.org/10.1186/s13048-024-01358-8

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