The impact of social protection interventions on treatment and socioeconomic outcomes of people with tuberculosis and their households: Protocol for a systematic review and meta-analysis [version 1; peer review: 2 approved, 1 approved with reservations]
Background: Tuberculosis (TB) is a leading cause of death due to infectious disease worldwide. People with TB and their households often suffer social and economic losses due to the cost of tuberculosis care. The World Health Organization 2015 End TB strategy called for socioeconomic support through...
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Wellcome
2023-04-01
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Series: | Wellcome Open Research |
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Online Access: | https://wellcomeopenresearch.org/articles/8-175/v1 |
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author | Delia Boccia Tom Wingfield Heather Todd Mollie Hudson Priya B. Shete Talemwa Nalugwa |
author_facet | Delia Boccia Tom Wingfield Heather Todd Mollie Hudson Priya B. Shete Talemwa Nalugwa |
author_sort | Delia Boccia |
collection | DOAJ |
description | Background: Tuberculosis (TB) is a leading cause of death due to infectious disease worldwide. People with TB and their households often suffer social and economic losses due to the cost of tuberculosis care. The World Health Organization 2015 End TB strategy called for socioeconomic support through social protection interventions. Social protection has the potential to enable people with TB and their households to break the cycle of TB and poverty, thereby improving both treatment and socioeconomic outcomes. This study aims to evaluate whether people with TB who are recipients of social protection interventions have better treatment and socioeconomic outcomes than those who are not recipients of social protection interventions. Methods: We will systematically review literature published in English between 2012 and 2021 from PubMed, Embase, and Web of Science, and grey literature from Google Scholar and selected, relevant databases. We will include studies that describe a social protection intervention (as defined by the World Bank) and report on TB treatment outcomes and/or socioeconomic outcomes. We will only include studies pertaining to populations in low-and-middle-income countries and/or countries with high TB burden. We will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Study quality will be assessed using the Cochrane Risk of Bias for randomized controlled trials and the Newcastle Ottawa Scale for non-randomised controlled studies. If sufficient quantitative data are available, we will perform a meta-analysis of aggregated outcomes. Lastly, we will use the Grading Recommendations Assessment, Development, and Evaluation to describe the overall quality of evidence. Ethics and dissemination: Ethical approval is not required for this systematic review, as all data extraction and analysis will be conducted on published documents. We will disseminate this protocol through conference presentations. The systematic review has been registered prospectively in the PROSPERO database (registration number CRD42022382181). |
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institution | Directory Open Access Journal |
issn | 2398-502X |
language | English |
last_indexed | 2024-03-11T23:15:42Z |
publishDate | 2023-04-01 |
publisher | Wellcome |
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series | Wellcome Open Research |
spelling | doaj.art-95e41f1dcc204226a29d876ec85964912023-09-21T01:00:01ZengWellcomeWellcome Open Research2398-502X2023-04-01820853The impact of social protection interventions on treatment and socioeconomic outcomes of people with tuberculosis and their households: Protocol for a systematic review and meta-analysis [version 1; peer review: 2 approved, 1 approved with reservations]Delia Boccia0https://orcid.org/0000-0001-9951-771XTom Wingfield1https://orcid.org/0000-0001-8433-6887Heather Todd2Mollie Hudson3https://orcid.org/0000-0001-8220-2834Priya B. Shete4Talemwa Nalugwa5Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UKDepartments of Clinical Sciences and International Public Health, Liverpool School of Tropical Medicine, Liverpool, UKDepartments of Clinical Sciences and International Public Health, Liverpool School of Tropical Medicine, Liverpool, UKSchool of Nursing, University of California, San Francisco, San Francisco, USADivision of Pulmonary and Critical Care Medicine, University of California, San Francisco, San Francisco, USAUganda Tuberculosis Implementation Research Consortium, Kampala, UgandaBackground: Tuberculosis (TB) is a leading cause of death due to infectious disease worldwide. People with TB and their households often suffer social and economic losses due to the cost of tuberculosis care. The World Health Organization 2015 End TB strategy called for socioeconomic support through social protection interventions. Social protection has the potential to enable people with TB and their households to break the cycle of TB and poverty, thereby improving both treatment and socioeconomic outcomes. This study aims to evaluate whether people with TB who are recipients of social protection interventions have better treatment and socioeconomic outcomes than those who are not recipients of social protection interventions. Methods: We will systematically review literature published in English between 2012 and 2021 from PubMed, Embase, and Web of Science, and grey literature from Google Scholar and selected, relevant databases. We will include studies that describe a social protection intervention (as defined by the World Bank) and report on TB treatment outcomes and/or socioeconomic outcomes. We will only include studies pertaining to populations in low-and-middle-income countries and/or countries with high TB burden. We will follow the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Study quality will be assessed using the Cochrane Risk of Bias for randomized controlled trials and the Newcastle Ottawa Scale for non-randomised controlled studies. If sufficient quantitative data are available, we will perform a meta-analysis of aggregated outcomes. Lastly, we will use the Grading Recommendations Assessment, Development, and Evaluation to describe the overall quality of evidence. Ethics and dissemination: Ethical approval is not required for this systematic review, as all data extraction and analysis will be conducted on published documents. We will disseminate this protocol through conference presentations. The systematic review has been registered prospectively in the PROSPERO database (registration number CRD42022382181).https://wellcomeopenresearch.org/articles/8-175/v1Tuberculosis social protection strategies social protection interventions socioeconomic support tuberculosis treatment success catastrophic costseng |
spellingShingle | Delia Boccia Tom Wingfield Heather Todd Mollie Hudson Priya B. Shete Talemwa Nalugwa The impact of social protection interventions on treatment and socioeconomic outcomes of people with tuberculosis and their households: Protocol for a systematic review and meta-analysis [version 1; peer review: 2 approved, 1 approved with reservations] Wellcome Open Research Tuberculosis social protection strategies social protection interventions socioeconomic support tuberculosis treatment success catastrophic costs eng |
title | The impact of social protection interventions on treatment and socioeconomic outcomes of people with tuberculosis and their households: Protocol for a systematic review and meta-analysis [version 1; peer review: 2 approved, 1 approved with reservations] |
title_full | The impact of social protection interventions on treatment and socioeconomic outcomes of people with tuberculosis and their households: Protocol for a systematic review and meta-analysis [version 1; peer review: 2 approved, 1 approved with reservations] |
title_fullStr | The impact of social protection interventions on treatment and socioeconomic outcomes of people with tuberculosis and their households: Protocol for a systematic review and meta-analysis [version 1; peer review: 2 approved, 1 approved with reservations] |
title_full_unstemmed | The impact of social protection interventions on treatment and socioeconomic outcomes of people with tuberculosis and their households: Protocol for a systematic review and meta-analysis [version 1; peer review: 2 approved, 1 approved with reservations] |
title_short | The impact of social protection interventions on treatment and socioeconomic outcomes of people with tuberculosis and their households: Protocol for a systematic review and meta-analysis [version 1; peer review: 2 approved, 1 approved with reservations] |
title_sort | impact of social protection interventions on treatment and socioeconomic outcomes of people with tuberculosis and their households protocol for a systematic review and meta analysis version 1 peer review 2 approved 1 approved with reservations |
topic | Tuberculosis social protection strategies social protection interventions socioeconomic support tuberculosis treatment success catastrophic costs eng |
url | https://wellcomeopenresearch.org/articles/8-175/v1 |
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