Carboplatin-Induced Bilateral Papilledema: A Case Report

We report on a patient with carboplatin-induced bilateral papilledema, as it was described in the 1970s for cisplatin. Loss of visual accuracy up to full blindness, often loss of color vision and scotomas can be seen as a result of cortical blindness, macula degeneration, retrobulbar neuritis and pa...

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Main Authors: N. Fischer, J. Stuermer, B. Rodic, M. Pless
Format: Article
Language:English
Published: Karger Publishers 2009-04-01
Series:Case Reports in Oncology
Subjects:
Online Access:http://www.karger.com/Article/FullText/212087
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author N. Fischer
J. Stuermer
B. Rodic
M. Pless
author_facet N. Fischer
J. Stuermer
B. Rodic
M. Pless
author_sort N. Fischer
collection DOAJ
description We report on a patient with carboplatin-induced bilateral papilledema, as it was described in the 1970s for cisplatin. Loss of visual accuracy up to full blindness, often loss of color vision and scotomas can be seen as a result of cortical blindness, macula degeneration, retrobulbar neuritis and papilledema. These symptoms are mostly unilateral and initially mild, so that more chemotherapy is given before the diagnosis is made. The symptoms are usually reversible within weeks to months after cessation of the platinum treatment. The therapeutic strategy is stopping the platinum treatment. In addition the empiric use of corticosteroids is suggested.
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spelling doaj.art-95e7b2ad819549f282667f0ce4bdc41e2022-12-21T18:18:32ZengKarger PublishersCase Reports in Oncology1662-65752009-04-0121677110.1159/000212087212087Carboplatin-Induced Bilateral Papilledema: A Case ReportN. FischerJ. StuermerB. RodicM. PlessWe report on a patient with carboplatin-induced bilateral papilledema, as it was described in the 1970s for cisplatin. Loss of visual accuracy up to full blindness, often loss of color vision and scotomas can be seen as a result of cortical blindness, macula degeneration, retrobulbar neuritis and papilledema. These symptoms are mostly unilateral and initially mild, so that more chemotherapy is given before the diagnosis is made. The symptoms are usually reversible within weeks to months after cessation of the platinum treatment. The therapeutic strategy is stopping the platinum treatment. In addition the empiric use of corticosteroids is suggested.http://www.karger.com/Article/FullText/212087CarboplatinCisplatinPapilledemaVisual impairment
spellingShingle N. Fischer
J. Stuermer
B. Rodic
M. Pless
Carboplatin-Induced Bilateral Papilledema: A Case Report
Case Reports in Oncology
Carboplatin
Cisplatin
Papilledema
Visual impairment
title Carboplatin-Induced Bilateral Papilledema: A Case Report
title_full Carboplatin-Induced Bilateral Papilledema: A Case Report
title_fullStr Carboplatin-Induced Bilateral Papilledema: A Case Report
title_full_unstemmed Carboplatin-Induced Bilateral Papilledema: A Case Report
title_short Carboplatin-Induced Bilateral Papilledema: A Case Report
title_sort carboplatin induced bilateral papilledema a case report
topic Carboplatin
Cisplatin
Papilledema
Visual impairment
url http://www.karger.com/Article/FullText/212087
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AT jstuermer carboplatininducedbilateralpapilledemaacasereport
AT brodic carboplatininducedbilateralpapilledemaacasereport
AT mpless carboplatininducedbilateralpapilledemaacasereport