Association Between Four Anthropometric Indexes and Metabolic Syndrome in US Adults
ObjectiveTo study the association between anthropometric indexes [lipid accumulation products (LAP), visceral obesity index (VAI), triglyceride and glucose index (TyG) and waist triglyceride index (WTI)] and metabolic syndrome (MetS) in a representative sample of American adult population surveyed b...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-05-01
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| Series: | Frontiers in Endocrinology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2022.889785/full |
| _version_ | 1811247384491982848 |
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| author | Yaling Li Rui Zheng Shuting Li Ruyi Cai Feihua Ni Huiyan Zheng Ruying Hu Ting Sun |
| author_facet | Yaling Li Rui Zheng Shuting Li Ruyi Cai Feihua Ni Huiyan Zheng Ruying Hu Ting Sun |
| author_sort | Yaling Li |
| collection | DOAJ |
| description | ObjectiveTo study the association between anthropometric indexes [lipid accumulation products (LAP), visceral obesity index (VAI), triglyceride and glucose index (TyG) and waist triglyceride index (WTI)] and metabolic syndrome (MetS) in a representative sample of American adult population surveyed by National Health and Nutrition Examination Survey (NHANES).MethodsCross-sectional data from the NHANES were used. Participants were adults aged 18–80 y from 1996–2006. MetS were defined by the updated National Cholesterol Education Program/Adult Treatment Panel III criteria (NCEP-ATP III) for Americans. Receiver operating characteristic (ROC) curve was drawn and the areas under the curve (AUC) were used to assess the ability of these indexes in screening MetS. Statistical differences among the AUC values of these indexes were compared. The association between the anthropometric indexes and MetS was investigated using weighted multivariable-adjusted logistic regression.Results560 (35.2%) males and 529 (26.4%) females were diagnosed with MetS. LAP was the strongest predictor of MetS for men (AUC=0.87, 95% CI 0.85-0.89), and also was the strongest for women [AUC=0.85, 95% confidence interval (CI) 0.83-0.86], according to the ROC curve analysis. In men, differences in AUC values between LAP and other anthropometric indicators were also significant (all P<0.001). In women, there was a significant difference in AUC values between LAP and WTI (P<0.001), but differences in AUC values between LAP and TyG, VAI were not significant.ConclusionThe present study indicated that LAP is a better predictor in the clinical setting for identifying individuals with MetS in the American adult population. |
| first_indexed | 2024-04-12T15:08:47Z |
| format | Article |
| id | doaj.art-95eaabe6bf2a466da891c0dafa8d01e3 |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-04-12T15:08:47Z |
| publishDate | 2022-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-95eaabe6bf2a466da891c0dafa8d01e32022-12-22T03:27:51ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922022-05-011310.3389/fendo.2022.889785889785Association Between Four Anthropometric Indexes and Metabolic Syndrome in US AdultsYaling Li0Rui Zheng1Shuting Li2Ruyi Cai3Feihua Ni4Huiyan Zheng5Ruying Hu6Ting Sun7Department Health Management Center, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, ChinaDepartment of Critical Care Medicine, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, ChinaDepartment Health Management Center, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, ChinaDepartment Health Management Center, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, ChinaDepartment Health Management Center, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, ChinaDepartment Health Management Center, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, ChinaDepartment Health Management Center, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, ChinaDepartment Health Management Center, the Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, ChinaObjectiveTo study the association between anthropometric indexes [lipid accumulation products (LAP), visceral obesity index (VAI), triglyceride and glucose index (TyG) and waist triglyceride index (WTI)] and metabolic syndrome (MetS) in a representative sample of American adult population surveyed by National Health and Nutrition Examination Survey (NHANES).MethodsCross-sectional data from the NHANES were used. Participants were adults aged 18–80 y from 1996–2006. MetS were defined by the updated National Cholesterol Education Program/Adult Treatment Panel III criteria (NCEP-ATP III) for Americans. Receiver operating characteristic (ROC) curve was drawn and the areas under the curve (AUC) were used to assess the ability of these indexes in screening MetS. Statistical differences among the AUC values of these indexes were compared. The association between the anthropometric indexes and MetS was investigated using weighted multivariable-adjusted logistic regression.Results560 (35.2%) males and 529 (26.4%) females were diagnosed with MetS. LAP was the strongest predictor of MetS for men (AUC=0.87, 95% CI 0.85-0.89), and also was the strongest for women [AUC=0.85, 95% confidence interval (CI) 0.83-0.86], according to the ROC curve analysis. In men, differences in AUC values between LAP and other anthropometric indicators were also significant (all P<0.001). In women, there was a significant difference in AUC values between LAP and WTI (P<0.001), but differences in AUC values between LAP and TyG, VAI were not significant.ConclusionThe present study indicated that LAP is a better predictor in the clinical setting for identifying individuals with MetS in the American adult population.https://www.frontiersin.org/articles/10.3389/fendo.2022.889785/fullmetabolic syndrometriglyceride and glucose index (TyG)adiposity index (VAI)lipid accumulation product (LAP)waist-triglyceride index (WTI)anthropometric indexes |
| spellingShingle | Yaling Li Rui Zheng Shuting Li Ruyi Cai Feihua Ni Huiyan Zheng Ruying Hu Ting Sun Association Between Four Anthropometric Indexes and Metabolic Syndrome in US Adults Frontiers in Endocrinology metabolic syndrome triglyceride and glucose index (TyG) adiposity index (VAI) lipid accumulation product (LAP) waist-triglyceride index (WTI) anthropometric indexes |
| title | Association Between Four Anthropometric Indexes and Metabolic Syndrome in US Adults |
| title_full | Association Between Four Anthropometric Indexes and Metabolic Syndrome in US Adults |
| title_fullStr | Association Between Four Anthropometric Indexes and Metabolic Syndrome in US Adults |
| title_full_unstemmed | Association Between Four Anthropometric Indexes and Metabolic Syndrome in US Adults |
| title_short | Association Between Four Anthropometric Indexes and Metabolic Syndrome in US Adults |
| title_sort | association between four anthropometric indexes and metabolic syndrome in us adults |
| topic | metabolic syndrome triglyceride and glucose index (TyG) adiposity index (VAI) lipid accumulation product (LAP) waist-triglyceride index (WTI) anthropometric indexes |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2022.889785/full |
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