Protocol for evaluation of tumor-derived exosome-induced cancer cell metastasis in a mouse model

Summary: Exosomes mediate intracellular communication between cancer cells and the local/distant microenvironment, which promotes systemic dissemination of cancer. Here, we present a protocol for tumor-derived exosome isolation and in vivo metastasis evaluation in a mouse model. We describe steps fo...

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Bibliographic Details
Main Authors: Yu Jin Lee, Kyeong Jin Shin, Young Chan Chae
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:STAR Protocols
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2666166723004112