Syntheses of Quinazoline-2,4-dione Alkaloids and Analogues from Mexican Zanthoxylum Species â€

Quinazolinone and quinazolinedione derivatives are of considerable interest due to their wide array of pharmacological properties. In this paper we report the synthesis of ten quinazolinediones. The previous isolation of two of these compounds, namely 1-methyl-3-(2'-phenylethyl)-1H,3H-quinazoli...

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Main Authors: R. Somanathan, K. Espinoza, I. A. Rivero
Format: Article
Language:English
Published: MDPI AG 2004-06-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/9/7/609/
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author R. Somanathan
K. Espinoza
I. A. Rivero
author_facet R. Somanathan
K. Espinoza
I. A. Rivero
author_sort R. Somanathan
collection DOAJ
description Quinazolinone and quinazolinedione derivatives are of considerable interest due to their wide array of pharmacological properties. In this paper we report the synthesis of ten quinazolinediones. The previous isolation of two of these compounds, namely 1-methyl-3-(2'-phenylethyl)-1H,3H-quinazoline-2,4-dione and 1-methyl-3-[2'-(4'- methoxyphenyl)ethyl]-lH,3H-quinazoline-2,4-dione, from the seed husks of Mexican Zanthoxylum species has been reported
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spelling doaj.art-95f31689588a4dc08ae2b54c0e4fb7c42022-12-22T02:04:01ZengMDPI AGMolecules1420-30492004-06-019760961610.3390/90700609Syntheses of Quinazoline-2,4-dione Alkaloids and Analogues from Mexican Zanthoxylum Species â€R. SomanathanK. EspinozaI. A. RiveroQuinazolinone and quinazolinedione derivatives are of considerable interest due to their wide array of pharmacological properties. In this paper we report the synthesis of ten quinazolinediones. The previous isolation of two of these compounds, namely 1-methyl-3-(2'-phenylethyl)-1H,3H-quinazoline-2,4-dione and 1-methyl-3-[2'-(4'- methoxyphenyl)ethyl]-lH,3H-quinazoline-2,4-dione, from the seed husks of Mexican Zanthoxylum species has been reportedhttp://www.mdpi.com/1420-3049/9/7/609/Quinazoline-24-dionealkaloidstriphosgeneanti-hypertensive activity.
spellingShingle R. Somanathan
K. Espinoza
I. A. Rivero
Syntheses of Quinazoline-2,4-dione Alkaloids and Analogues from Mexican Zanthoxylum Species â€
Molecules
Quinazoline-2
4-dione
alkaloids
triphosgene
anti-hypertensive activity.
title Syntheses of Quinazoline-2,4-dione Alkaloids and Analogues from Mexican Zanthoxylum Species â€
title_full Syntheses of Quinazoline-2,4-dione Alkaloids and Analogues from Mexican Zanthoxylum Species â€
title_fullStr Syntheses of Quinazoline-2,4-dione Alkaloids and Analogues from Mexican Zanthoxylum Species â€
title_full_unstemmed Syntheses of Quinazoline-2,4-dione Alkaloids and Analogues from Mexican Zanthoxylum Species â€
title_short Syntheses of Quinazoline-2,4-dione Alkaloids and Analogues from Mexican Zanthoxylum Species â€
title_sort syntheses of quinazoline 2 4 dione alkaloids and analogues from mexican zanthoxylum species a¢a€
topic Quinazoline-2
4-dione
alkaloids
triphosgene
anti-hypertensive activity.
url http://www.mdpi.com/1420-3049/9/7/609/
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