Farnesol Protects against Cardiotoxicity Caused by Doxorubicin-Induced Stress, Inflammation, and Cell Death: An In Vivo Study in Wistar Rats

Farnesol Protects against Cardiotoxicity Caused by Doxorubicin-Induced Stress, Inflammation, and Cell Death: An In Vivo Study in Wistar Rats

Doxorubicin (DOXO) is an antineoplastic drug that is used extensively in managing multiple cancer types. However, DOXO-induced cardiotoxicity is a limiting factor for its widespread use and considerably affects patients’ quality of life. Farnesol (FSN) is a sesquiterpene with antioxidant, anti-infla...

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Bibliographic Details
Main Authors: Abdulrab Ahmed M. Alkhanjaf, Md Tanwir Athar, Zabih Ullah, Abdullah Mohammed H. Alsayhab, Ahmad Umar, Ibrahim Ahmed Shaikh
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Molecules
Subjects:
farnesol
reactive oxygen species
caspase-3
NF-kB
inflammation
cardioprotection
Online Access:https://www.mdpi.com/1420-3049/27/23/8589

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