Recognizing puzzling PD1 + infiltrates in marginal zone lymphoma by integrating clonal and mutational findings: pitfalls in both nodal and transformed splenic cases

Recognizing puzzling PD1 + infiltrates in marginal zone lymphoma by integrating clonal and mutational findings: pitfalls in both nodal and transformed splenic cases

Abstract Background A marked increase in PD1-positive TFH cells in nodal MZL cases (NMZL) was reported previously and could prompt suspicion for a diagnosis of peripheral T-cell lymphoma (PTCL), especially angioimmunoblastic T-cell lymphoma (AITL). Case presentation To demonstrate that the pitfall m...

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Bibliographic Details
Main Authors: Jili Deng, Youjun Cao, Xinting Diao, Meng Wu, Xianghong Li, Yunfei Shi
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Diagnostic Pathology
Subjects:
Clonality
Genetic mutation
Marginal zone lymphoma
PD1
Pitfall
T cell
Online Access:https://doi.org/10.1186/s13000-023-01422-9

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