Effect of berberine on irritable bowel syndrome: A symptom-based review
Phytotherapeutic applications have gained a place in the symptomatic treatment of irritable bowel syndrome, one of the most common diseases globally among functional bowel diseases. This study aimed to compile evidence regarding the efficacy of berberine in relieving the symptoms of irritable bowel...
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| Format: | Article |
| Language: | English |
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Bektas Tepe
2022-04-01
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| Series: | International Journal of Plant Based Pharmaceuticals |
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| Online Access: | https://ijpbp.com/index.php/ijpbp/article/view/37 |
| _version_ | 1797752348986048512 |
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| author | Ibrahim Bashan |
| author_facet | Ibrahim Bashan |
| author_sort | Ibrahim Bashan |
| collection | DOAJ |
| description | Phytotherapeutic applications have gained a place in the symptomatic treatment of irritable bowel syndrome, one of the most common diseases globally among functional bowel diseases. This study aimed to compile evidence regarding the efficacy of berberine in relieving the symptoms of irritable bowel syndrome. In this review, the electronic databases of PubMed, Google Scholar, MEDLINE, and Web of Science were used, and current publications were searched without any language restrictions. The screening was performed by first performing a general search using the keyword "berberine and irritable bowel syndrome", followed by individual searches for each symptom. Although there are many preclinical studies investigating the effect of berberine on the gastrointestinal tract, human studies are still limited. Studies show that berberine may positively affect abdominal pain, diarrhea, inflammation, microbiota, and visceral hypersensitivity, although the mechanisms of action are not yet clear. However, available data suggest that the therapeutic use of berberine in irritable bowel syndrome may be limited to the predominant type of diarrhea and selected patients whose symptoms are evaluated individually. Evidence presented in this paper needs to be further supported by human clinical studies. |
| first_indexed | 2024-03-12T17:02:01Z |
| format | Article |
| id | doaj.art-95f5c8004a214327a40356e6352d5738 |
| institution | Directory Open Access Journal |
| issn | 2791-7509 |
| language | English |
| last_indexed | 2024-03-12T17:02:01Z |
| publishDate | 2022-04-01 |
| publisher | Bektas Tepe |
| record_format | Article |
| series | International Journal of Plant Based Pharmaceuticals |
| spelling | doaj.art-95f5c8004a214327a40356e6352d57382023-08-07T09:56:15ZengBektas TepeInternational Journal of Plant Based Pharmaceuticals2791-75092022-04-012219019510.55484/ijpbp.108445537Effect of berberine on irritable bowel syndrome: A symptom-based reviewIbrahim Bashan0https://orcid.org/0000-0002-0034-2727Mersin University, Medical Faculty of Mersin University, Department of Medical Education, 33343, Mersin, TurkeyPhytotherapeutic applications have gained a place in the symptomatic treatment of irritable bowel syndrome, one of the most common diseases globally among functional bowel diseases. This study aimed to compile evidence regarding the efficacy of berberine in relieving the symptoms of irritable bowel syndrome. In this review, the electronic databases of PubMed, Google Scholar, MEDLINE, and Web of Science were used, and current publications were searched without any language restrictions. The screening was performed by first performing a general search using the keyword "berberine and irritable bowel syndrome", followed by individual searches for each symptom. Although there are many preclinical studies investigating the effect of berberine on the gastrointestinal tract, human studies are still limited. Studies show that berberine may positively affect abdominal pain, diarrhea, inflammation, microbiota, and visceral hypersensitivity, although the mechanisms of action are not yet clear. However, available data suggest that the therapeutic use of berberine in irritable bowel syndrome may be limited to the predominant type of diarrhea and selected patients whose symptoms are evaluated individually. Evidence presented in this paper needs to be further supported by human clinical studies.https://ijpbp.com/index.php/ijpbp/article/view/37diarrheaabdominal painmotilityphytotherapy |
| spellingShingle | Ibrahim Bashan Effect of berberine on irritable bowel syndrome: A symptom-based review International Journal of Plant Based Pharmaceuticals diarrhea abdominal pain motility phytotherapy |
| title | Effect of berberine on irritable bowel syndrome: A symptom-based review |
| title_full | Effect of berberine on irritable bowel syndrome: A symptom-based review |
| title_fullStr | Effect of berberine on irritable bowel syndrome: A symptom-based review |
| title_full_unstemmed | Effect of berberine on irritable bowel syndrome: A symptom-based review |
| title_short | Effect of berberine on irritable bowel syndrome: A symptom-based review |
| title_sort | effect of berberine on irritable bowel syndrome a symptom based review |
| topic | diarrhea abdominal pain motility phytotherapy |
| url | https://ijpbp.com/index.php/ijpbp/article/view/37 |
| work_keys_str_mv | AT ibrahimbashan effectofberberineonirritablebowelsyndromeasymptombasedreview |