Antihypertensive therapy and left ventricular hypertrophy prevention in patients with essential arterial hypertension and high treatment compliance

Aim. To investigate the features of antihypertensive therapy (AHT), as a method of left ventricular hypertrophy (LVH) prevention, in patients with essential arterial hypertension (EAH), absence of target organ damage (TOD), and high treatment compliance. Material and methods. This prospective cohort...

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Main Authors: N. A. Koziolova, I. M. Shatunova, I. A. Lazarev
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 1970-01-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/1987
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author N. A. Koziolova
I. M. Shatunova
I. A. Lazarev
author_facet N. A. Koziolova
I. M. Shatunova
I. A. Lazarev
author_sort N. A. Koziolova
collection DOAJ
description Aim. To investigate the features of antihypertensive therapy (AHT), as a method of left ventricular hypertrophy (LVH) prevention, in patients with essential arterial hypertension (EAH), absence of target organ damage (TOD), and high treatment compliance. Material and methods. This prospective cohort study included 428 patients with EAH and no TOD (mean followup 8,8±2,6 years). Results. In patients with EAH, and high treatment compliance, LVH incidence was 36,9 %. AHT was more aggressive in patients with LV remodelling, and was characterised by higher rates of combined treatment or b-adrenoblocker treatment. Conclusion. In EAH patients with high treatment compliance, LVH incidence was lower than in general population. More aggressive AHT among patients with LVH could be explained by potential therapy resistance in this clinical group.
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spelling doaj.art-95f6863865f243c1b08d409fe6f6643d2023-03-13T07:23:10Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01251970-01-01107491699Antihypertensive therapy and left ventricular hypertrophy prevention in patients with essential arterial hypertension and high treatment complianceN. A. Koziolova0I. M. Shatunova1I. A. Lazarev2Пермская государственная медицинская академия имени академика Е.А. ВагнераПоликлиника ОАО “ГАЗПРОМ”Поликлиника ОАО “ГАЗПРОМ”Aim. To investigate the features of antihypertensive therapy (AHT), as a method of left ventricular hypertrophy (LVH) prevention, in patients with essential arterial hypertension (EAH), absence of target organ damage (TOD), and high treatment compliance. Material and methods. This prospective cohort study included 428 patients with EAH and no TOD (mean followup 8,8±2,6 years). Results. In patients with EAH, and high treatment compliance, LVH incidence was 36,9 %. AHT was more aggressive in patients with LV remodelling, and was characterised by higher rates of combined treatment or b-adrenoblocker treatment. Conclusion. In EAH patients with high treatment compliance, LVH incidence was lower than in general population. More aggressive AHT among patients with LVH could be explained by potential therapy resistance in this clinical group.https://cardiovascular.elpub.ru/jour/article/view/1987гипертоническая болезньгипертрофия миокарда левого желудочкаприверженность лечениюантигипертензивная терапияb-адреноблокаторыпрофилактика
spellingShingle N. A. Koziolova
I. M. Shatunova
I. A. Lazarev
Antihypertensive therapy and left ventricular hypertrophy prevention in patients with essential arterial hypertension and high treatment compliance
Кардиоваскулярная терапия и профилактика
гипертоническая болезнь
гипертрофия миокарда левого желудочка
приверженность лечению
антигипертензивная терапия
b-адреноблокаторы
профилактика
title Antihypertensive therapy and left ventricular hypertrophy prevention in patients with essential arterial hypertension and high treatment compliance
title_full Antihypertensive therapy and left ventricular hypertrophy prevention in patients with essential arterial hypertension and high treatment compliance
title_fullStr Antihypertensive therapy and left ventricular hypertrophy prevention in patients with essential arterial hypertension and high treatment compliance
title_full_unstemmed Antihypertensive therapy and left ventricular hypertrophy prevention in patients with essential arterial hypertension and high treatment compliance
title_short Antihypertensive therapy and left ventricular hypertrophy prevention in patients with essential arterial hypertension and high treatment compliance
title_sort antihypertensive therapy and left ventricular hypertrophy prevention in patients with essential arterial hypertension and high treatment compliance
topic гипертоническая болезнь
гипертрофия миокарда левого желудочка
приверженность лечению
антигипертензивная терапия
b-адреноблокаторы
профилактика
url https://cardiovascular.elpub.ru/jour/article/view/1987
work_keys_str_mv AT nakoziolova antihypertensivetherapyandleftventricularhypertrophypreventioninpatientswithessentialarterialhypertensionandhightreatmentcompliance
AT imshatunova antihypertensivetherapyandleftventricularhypertrophypreventioninpatientswithessentialarterialhypertensionandhightreatmentcompliance
AT ialazarev antihypertensivetherapyandleftventricularhypertrophypreventioninpatientswithessentialarterialhypertensionandhightreatmentcompliance