Epidemiological and molecular-genetic monitoring of rotavirus infection in the Orenburg region in the period predictively
Aim. To analyze the epidemiological situation of rotavirus infection in the Orenburg region, taking into account the manifestations of the epidemic process and the molecular genetic characteristics of rotavirus group. Materials and methods. We рresented the results of epidemiological and molecu...
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| Format: | Article |
| Language: | Russian |
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Central Research Institute for Epidemiology
2019-08-01
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| Series: | Журнал микробиологии, эпидемиологии и иммунобиологии |
| Subjects: | |
| Online Access: | https://microbiol.elpub.ru/jour/article/view/379 |
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| author | V. G. Akimkin A. V. Gorelov A. T. Podkolzin N. B. Denisyuk |
| author_facet | V. G. Akimkin A. V. Gorelov A. T. Podkolzin N. B. Denisyuk |
| author_sort | V. G. Akimkin |
| collection | DOAJ |
| description | Aim. To analyze the epidemiological situation of rotavirus infection in the Orenburg region, taking into account the manifestations of the epidemic process and the molecular genetic characteristics of rotavirus group. Materials and methods. We рresented the results of epidemiological and molecular genetic monitoring of rotavirus infection in the period 2013-2017. Molecular genetic typing was performed in 232 fecal samples of patients under 3 years of age with rotavirus infection. Were used methods of retrospective epidemiological analysis, ELISA, PCR. Results. The incidence of high tear and had a tendency to increase. The most affected were children under 14 years of age. The genetic potential of the rotavirus population in the region was represented by ten main genotypes. The leading significance in the epidemic process were genotypes with the highest frequency of occurrence: G4[P]8 (56,9%), G9[P]8 (12,9%), Mixt (8,6%), G2[P]4 (7,7%), G1[P]8 (6,5%). Conclusion. Were revealed a significant increase in the incidence of rotavirus infection among children. Were revealed the dominant genotypes of rotaviruses, their regional diversity and change during several seasons. |
| first_indexed | 2024-04-11T21:10:02Z |
| format | Article |
| id | doaj.art-95f8d0f536b84000804cb13ce92382b0 |
| institution | Directory Open Access Journal |
| issn | 0372-9311 2686-7613 |
| language | Russian |
| last_indexed | 2024-04-11T21:10:02Z |
| publishDate | 2019-08-01 |
| publisher | Central Research Institute for Epidemiology |
| record_format | Article |
| series | Журнал микробиологии, эпидемиологии и иммунобиологии |
| spelling | doaj.art-95f8d0f536b84000804cb13ce92382b02022-12-22T04:03:04ZrusCentral Research Institute for EpidemiologyЖурнал микробиологии, эпидемиологии и иммунобиологии0372-93112686-76132019-08-0102303610.36233/0372-9311-2019-2-30-36371Epidemiological and molecular-genetic monitoring of rotavirus infection in the Orenburg region in the period predictivelyV. G. Akimkin0A. V. Gorelov1A. T. Podkolzin2N. B. Denisyuk3Central Research Institute of EpidemiologyCentral Research Institute of EpidemiologyCentral Research Institute of EpidemiologyOrenburg State Medical UniversityAim. To analyze the epidemiological situation of rotavirus infection in the Orenburg region, taking into account the manifestations of the epidemic process and the molecular genetic characteristics of rotavirus group. Materials and methods. We рresented the results of epidemiological and molecular genetic monitoring of rotavirus infection in the period 2013-2017. Molecular genetic typing was performed in 232 fecal samples of patients under 3 years of age with rotavirus infection. Were used methods of retrospective epidemiological analysis, ELISA, PCR. Results. The incidence of high tear and had a tendency to increase. The most affected were children under 14 years of age. The genetic potential of the rotavirus population in the region was represented by ten main genotypes. The leading significance in the epidemic process were genotypes with the highest frequency of occurrence: G4[P]8 (56,9%), G9[P]8 (12,9%), Mixt (8,6%), G2[P]4 (7,7%), G1[P]8 (6,5%). Conclusion. Were revealed a significant increase in the incidence of rotavirus infection among children. Were revealed the dominant genotypes of rotaviruses, their regional diversity and change during several seasons.https://microbiol.elpub.ru/jour/article/view/379genotypeschildrenmorbidityrotavirus infection |
| spellingShingle | V. G. Akimkin A. V. Gorelov A. T. Podkolzin N. B. Denisyuk Epidemiological and molecular-genetic monitoring of rotavirus infection in the Orenburg region in the period predictively Журнал микробиологии, эпидемиологии и иммунобиологии genotypes children morbidity rotavirus infection |
| title | Epidemiological and molecular-genetic monitoring of rotavirus infection in the Orenburg region in the period predictively |
| title_full | Epidemiological and molecular-genetic monitoring of rotavirus infection in the Orenburg region in the period predictively |
| title_fullStr | Epidemiological and molecular-genetic monitoring of rotavirus infection in the Orenburg region in the period predictively |
| title_full_unstemmed | Epidemiological and molecular-genetic monitoring of rotavirus infection in the Orenburg region in the period predictively |
| title_short | Epidemiological and molecular-genetic monitoring of rotavirus infection in the Orenburg region in the period predictively |
| title_sort | epidemiological and molecular genetic monitoring of rotavirus infection in the orenburg region in the period predictively |
| topic | genotypes children morbidity rotavirus infection |
| url | https://microbiol.elpub.ru/jour/article/view/379 |
| work_keys_str_mv | AT vgakimkin epidemiologicalandmoleculargeneticmonitoringofrotavirusinfectionintheorenburgregionintheperiodpredictively AT avgorelov epidemiologicalandmoleculargeneticmonitoringofrotavirusinfectionintheorenburgregionintheperiodpredictively AT atpodkolzin epidemiologicalandmoleculargeneticmonitoringofrotavirusinfectionintheorenburgregionintheperiodpredictively AT nbdenisyuk epidemiologicalandmoleculargeneticmonitoringofrotavirusinfectionintheorenburgregionintheperiodpredictively |