Immunogenicity and Protective Efficacy of Seasonal Human Live Attenuated Cold-Adapted Influenza Virus Vaccine in Pigs

Immunogenicity and Protective Efficacy of Seasonal Human Live Attenuated Cold-Adapted Influenza Virus Vaccine in Pigs

Influenza A virus infection is a global health threat to livestock and humans, causing substantial mortality and morbidity. As both pigs and humans are readily infected with influenza viruses of similar subtype, the pig is a robust and appropriate model for investigating swine and human disease. We...

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Bibliographic Details
Main Authors: Barbara Holzer, Sophie B. Morgan, Veronica Martini, Rajni Sharma, Becky Clark, Christopher Chiu, Francisco J. Salguero, Elma Tchilian
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Immunology
Subjects:
LAIV (live attenuated influenza vaccine)
pig
influenza virus
T cell responses
mucosal immunity
antibody responses
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02625/full

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