Antibody-mediated depletion of select leukocyte subsets in blood and tissue of nonhuman primates

Antibody-mediated depletion of select leukocyte subsets in blood and tissue of nonhuman primates

Understanding the immunological control of pathogens requires a detailed evaluation of the mechanistic contributions of individual cell types within the immune system. While knockout mouse models that lack certain cell types have been used to help define the role of those cells, the biological and p...

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Bibliographic Details
Main Authors: Matthew S. Sutton, Allison N. Bucsan, Chelsea C. Lehman, Megha Kamath, Supriya Pokkali, Diogo M. Magnani, Robert Seder, Patricia A. Darrah, Mario Roederer
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-03-01
Series:Frontiers in Immunology
Subjects:
in vivo depletion
nonhuman primates
MT807R1
CD4R1
CD8β255R1
C207
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1359679/full

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