CMV Colitis: A Rare Complication of Azacitidine and Venetoclax Chemotherapy

Herein, we present a case of cytomegalovirus (CMV) colitis that occurred after two cycles of azacitidine and venetoclax in a 64-year-old woman affected with acute myeloid leukaemia (AML) secondary to a previous diagnosis of a hypoplastic myelodysplastic syndrome (hypo-MDS). This patient never had de...

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Bibliographic Details
Main Authors: Mustafa Nissar Bankur, Archie Keeling, Khoodoruth Mohamed Adil Shah, Daniele Avenoso
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Hematology Reports
Subjects:
Online Access:https://www.mdpi.com/2038-8330/14/3/29
Description
Summary:Herein, we present a case of cytomegalovirus (CMV) colitis that occurred after two cycles of azacitidine and venetoclax in a 64-year-old woman affected with acute myeloid leukaemia (AML) secondary to a previous diagnosis of a hypoplastic myelodysplastic syndrome (hypo-MDS). This patient never had detectable CMV viraemia, and there was no evidence of immune deficiency that could justify this opportunistic infection. Additionally, this is most likely the first report describing CMV colitis in a patient treated upfront with azacitidine and venetoclax.
ISSN:2038-8330