Lamellar projections in the endolymphatic sac act as a relief valve to regulate inner ear pressure

Lamellar projections in the endolymphatic sac act as a relief valve to regulate inner ear pressure

The inner ear is a fluid-filled closed-epithelial structure whose function requires maintenance of an internal hydrostatic pressure and fluid composition. The endolymphatic sac (ES) is a dead-end epithelial tube connected to the inner ear whose function is unclear. ES defects can cause distended ear...

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Bibliographic Details
Main Authors: Ian A Swinburne, Kishore R Mosaliganti, Srigokul Upadhyayula, Tsung-Li Liu, David G C Hildebrand, Tony Y -C Tsai, Anzhi Chen, Ebaa Al-Obeidi, Anna K Fass, Samir Malhotra, Florian Engert, Jeff W Lichtman, Tomas Kirchhausen, Eric Betzig, Sean G Megason
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-06-01
Series:eLife
Subjects:
inner ear
pressure
timelapse
lamella
valve
Online Access:https://elifesciences.org/articles/37131

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