Mesenchymal stem cell-derived exosomal microRNA-367–3p alleviates experimental autoimmune encephalomyelitis via inhibition of microglial ferroptosis by targeting EZH2

Mesenchymal stem cell-derived exosomal microRNA-367–3p alleviates experimental autoimmune encephalomyelitis via inhibition of microglial ferroptosis by targeting EZH2

Multiple sclerosis (MS) is an autoimmune, inflammatory demyelinating disorder of the central nervous system. Accumulating evidence has underscored the therapeutic potential of bone marrow mesenchymal stem cells (BMSCs)-derived exosomes (BMSC-Exos) containing bioactive compounds in MS. Herein, the cu...

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Bibliographic Details
Main Authors: Jingyi Fan, Yusen Han, Huanhuan Sun, Shichao Sun, Ying Wang, Ruoyi Guo, Jiangyuan Guo, Xinyi Tian, Jinli Wang, Jueqiong Wang
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Bone mesenchymal stem cells
Exosome
Experimental autoimmune encephalomyelitis
MicroRNA-367–3p
EZH2
SLC7A11
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223003815

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