Liraglutide modulates GABAergic signaling in rat hippocampal CA3 pyramidal neurons predominantly by presynaptic mechanism

Abstract Background γ-Aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the brain where it regulates activity of neuronal networks. The receptor for glucagon-like peptide-1 (GLP-1) is expressed in the hippocampus, which is the center for memory and learning. In this study we examin...

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Bibliographic Details
Main Authors: Omar Babateen, Sergiy V. Korol, Zhe Jin, Amol K. Bhandage, Aikeremu Ahemaiti, Bryndis Birnir
Format: Article
Language:English
Published: BMC 2017-12-01
Series:BMC Pharmacology and Toxicology
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Online Access:http://link.springer.com/article/10.1186/s40360-017-0191-0

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