Effect of HPSE and HPSE2 SNPs on the Risk of Developing Primary Paraskeletal Multiple Myeloma

Effect of HPSE and HPSE2 SNPs on the Risk of Developing Primary Paraskeletal Multiple Myeloma

Multiple myeloma (MM) is a plasma cell malignancy that is accompanied by hypercalcemia, renal failure, anemia, and lytic bone lesions. Heparanase (HPSE) plays an important role in supporting and promoting myeloma progression, maintenance of plasma cell stemness, and resistance to therapy. Previous s...

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Bibliographic Details
Main Authors:	Olga Ostrovsky, Katia Beider, Hila Magen, Merav Leiba, Ralph D. Sanderson, Israel Vlodavsky, Arnon Nagler
Format:	Article
Language:	English
Published:	MDPI AG 2023-03-01
Series:	Cells
Subjects:	HPSE gene HPSE2 gene SNPs multiple myeloma extramedullary disease
Online Access:	https://www.mdpi.com/2073-4409/12/6/913

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