Neonatal susceptibility to meningitis results from the immaturity of epithelial barriers and gut microbiota

Neonatal susceptibility to meningitis results from the immaturity of epithelial barriers and gut microbiota

Summary: Neonates are highly susceptible to bacterial meningitis as compared to children and adults. Group B streptococcus (GBS) is a major cause of neonatal meningitis. Neonatal meningitis can result from GBS intestinal colonization and translocation across the intestinal barrier (IB). Here, we sho...

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Bibliographic Details
Main Authors: Laetitia Travier, Mariana Alonso, Alessio Andronico, Lukas Hafner, Olivier Disson, Pierre-Marie Lledo, Simon Cauchemez, Marc Lecuit
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Cell Reports
Subjects:
infection
intestine
neonatal
meningitis
choroid plexus
intestinal barrier
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721006951

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