Atovaquone inhibits colorectal cancer metastasis by regulating PDGFRβ/NF-κB signaling pathway

Atovaquone inhibits colorectal cancer metastasis by regulating PDGFRβ/NF-κB signaling pathway

Abstract Background Colorectal cancer is a common malignant tumour. Invasive growth and distant metastasis are the main characteristics of its malignant biological behaviour, and they are also the primary factors leading to death in colon cancer patients. Atovaquone is an antimalarial drug, and its...

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Bibliographic Details
Main Authors: Bin Liu, Xin Zheng, Jiajun Li, Peng Yao, Peng Guo, Wei Liu, Gaoping Zhao
Format: Article
Language:English
Published: BMC 2023-11-01
Series:BMC Cancer
Subjects:
Atovaquone
Colorectal cancer
Metastasis
PDGFRβ
NF-κB
Online Access:https://doi.org/10.1186/s12885-023-11585-9

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