Procognitive, Anxiolytic, and Antidepressant-like Properties of Hyperoside and Protocatechuic Acid Corresponding with the Increase in Serum Serotonin Level after Prolonged Treatment in Mice

Procognitive, Anxiolytic, and Antidepressant-like Properties of Hyperoside and Protocatechuic Acid Corresponding with the Increase in Serum Serotonin Level after Prolonged Treatment in Mice

Two polyphenols–hyperoside (HYP) and protocatechuic acid (PCA) were reported to exert antidepressant activity in rodents after acute treatment. Our previous study also showed that this activity might have been influenced by the monoaminergic system and the upregulation of the brain-derived neurotrop...

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Main Authors: Jolanta Orzelska-Górka, Katarzyna Dos Santos Szewczyk, Monika Gawrońska-Grzywacz, Mariola Herbet, Anna Lesniak, Anna Bielenica, Magdalena Bujalska-Zadrożny, Grażyna Biała
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Pharmaceuticals
Subjects:
hyperoside
protocatechuic acid
antidepressant
anxiolytic
procognitive
mice
Online Access:https://www.mdpi.com/1424-8247/16/12/1691

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