Neurological Complications of Biological Treatment of Psoriasis

In the available literature, little attention has been paid to the assessment of psoriasis and the biological therapy used for it and the nervous system. The purpose of this article is to discuss the relationship between psoriasis and the nervous system as well as to analyze the mechanisms that lead...

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Main Authors: Mateusz Kamil Ożóg, Beniamin Oskar Grabarek, Magdalena Wierzbik-Strońska, Magdalena Świder
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/12/1/118
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author Mateusz Kamil Ożóg
Beniamin Oskar Grabarek
Magdalena Wierzbik-Strońska
Magdalena Świder
author_facet Mateusz Kamil Ożóg
Beniamin Oskar Grabarek
Magdalena Wierzbik-Strońska
Magdalena Świder
author_sort Mateusz Kamil Ożóg
collection DOAJ
description In the available literature, little attention has been paid to the assessment of psoriasis and the biological therapy used for it and the nervous system. The purpose of this article is to discuss the relationship between psoriasis and the nervous system as well as to analyze the mechanisms that lead to neurological complications during anticytokine therapies in psoriasis. However, this connection requires further analysis. The use of biological drugs in psoriasis, although it yields positive therapeutic results, is not without numerous side effects. Serious neurological side effects of the therapy are most often visible with the use of anti-TNF-alpha, which is why patients should be monitored for their potential occurrence. Early detection of complications and rapid discontinuation of treatment with the drug may potentially increase the patient’s chances of a full recovery or improvement of his/her neurological condition. It also seems reasonable that, in the case of complications occurring during anti-TNF-alpha therapy, some of the drugs from other groups should be included in the therapy.
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spelling doaj.art-961021d4aa3f46278aa6b4a221fb6a942023-11-23T14:25:19ZengMDPI AGLife2075-17292022-01-0112111810.3390/life12010118Neurological Complications of Biological Treatment of PsoriasisMateusz Kamil Ożóg0Beniamin Oskar Grabarek1Magdalena Wierzbik-Strońska2Magdalena Świder3Department of Histology, Cytophysiology and Embryology, Faculty of Medicine, University of Technology in Katowice, 41-800 Zabrze, PolandDepartment of Histology, Cytophysiology and Embryology, Faculty of Medicine, University of Technology in Katowice, 41-800 Zabrze, PolandFaculty of Medicine, University of Technology in Katowice, 41-800 Zabrze, PolandDepartment of Histology, Cytophysiology and Embryology, Faculty of Medicine, University of Technology in Katowice, 41-800 Zabrze, PolandIn the available literature, little attention has been paid to the assessment of psoriasis and the biological therapy used for it and the nervous system. The purpose of this article is to discuss the relationship between psoriasis and the nervous system as well as to analyze the mechanisms that lead to neurological complications during anticytokine therapies in psoriasis. However, this connection requires further analysis. The use of biological drugs in psoriasis, although it yields positive therapeutic results, is not without numerous side effects. Serious neurological side effects of the therapy are most often visible with the use of anti-TNF-alpha, which is why patients should be monitored for their potential occurrence. Early detection of complications and rapid discontinuation of treatment with the drug may potentially increase the patient’s chances of a full recovery or improvement of his/her neurological condition. It also seems reasonable that, in the case of complications occurring during anti-TNF-alpha therapy, some of the drugs from other groups should be included in the therapy.https://www.mdpi.com/2075-1729/12/1/118psoriasisbiological treatmentanticytokine therapytumor necrosis factor alphanervous systemside effects
spellingShingle Mateusz Kamil Ożóg
Beniamin Oskar Grabarek
Magdalena Wierzbik-Strońska
Magdalena Świder
Neurological Complications of Biological Treatment of Psoriasis
Life
psoriasis
biological treatment
anticytokine therapy
tumor necrosis factor alpha
nervous system
side effects
title Neurological Complications of Biological Treatment of Psoriasis
title_full Neurological Complications of Biological Treatment of Psoriasis
title_fullStr Neurological Complications of Biological Treatment of Psoriasis
title_full_unstemmed Neurological Complications of Biological Treatment of Psoriasis
title_short Neurological Complications of Biological Treatment of Psoriasis
title_sort neurological complications of biological treatment of psoriasis
topic psoriasis
biological treatment
anticytokine therapy
tumor necrosis factor alpha
nervous system
side effects
url https://www.mdpi.com/2075-1729/12/1/118
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AT magdalenawierzbikstronska neurologicalcomplicationsofbiologicaltreatmentofpsoriasis
AT magdalenaswider neurologicalcomplicationsofbiologicaltreatmentofpsoriasis