Bacterial OTU deubiquitinases regulate substrate ubiquitination upon Legionella infection

Bacterial OTU deubiquitinases regulate substrate ubiquitination upon Legionella infection

Legionella pneumophila causes a severe pneumonia known as Legionnaires’ disease. During the infection, Legionella injects more than 300 effector proteins into host cells. Among them are enzymes involved in altering the host-ubiquitination system. Here, we identified two LegionellaOTU (ovarian tumor)...

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Bibliographic Details
Main Authors: Donghyuk Shin, Anshu Bhattacharya, Yi-Lin Cheng, Marta Campos Alonso, Ahmad Reza Mehdipour, Gerbrand J van der Heden van Noort, Huib Ovaa, Gerhard Hummer, Ivan Dikic
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-11-01
Series:eLife
Subjects:
bacterial deubiquitinase
Legionella pneumophila
effector proteins
ubiquitin
OTU-deubiquitinase
Online Access:https://elifesciences.org/articles/58277

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