New Insight into the Substrate Selectivity of Bovine Milk γ-glutamyl Transferase via Structural and Molecular Dynamics Predictions

New Insight into the Substrate Selectivity of Bovine Milk γ-glutamyl Transferase via Structural and Molecular Dynamics Predictions

Bovine milk γ-glutamyltransferase (BoGGT) can produce γ-glutamyl peptides using L-glutamine as a donor substrate, and the transpeptidase activity is highly dependent on both γ-glutamyl donors and acceptors. To explore the molecular mechanism behind the donor and acceptor substrate preferences for Bo...

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Bibliographic Details
Main Authors:	Lichuang Cao, Cameron J. Hunt, Anne S. Meyer, René Lametsch
Format:	Article
Language:	English
Published:	MDPI AG 2023-06-01
Series:	Molecules
Subjects:	γ-glutamyl donor γ-glutamyl acceptor molecular docking γ-glutamyl-enzyme intermediate molecular dynamic simulation
Online Access:	https://www.mdpi.com/1420-3049/28/12/4657

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