Isolated trisomy 11 in de novo acute myeloid leukemia Trissomia 11 isolada em leucemia mielóide aguda de novo
The real mechanism involved in trisomies and leukemogenesis remains unknown and more information about this connection is essential, but unfortunately the clinical outcome and hematological profile of patients with isolated trisomy 11 and AML have not been well characterized. Considering the limited...
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| Format: | Article |
| Language: | English |
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Elsevier
2008-01-01
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| Series: | Revista Brasileira de Hematologia e Hemoterapia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842008000300016 |
| _version_ | 1818508398932525056 |
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| author | Everson A. Krum Tatiane Hamed Mihoko Yamamoto Maria de Lourdes Chauffaille |
| author_facet | Everson A. Krum Tatiane Hamed Mihoko Yamamoto Maria de Lourdes Chauffaille |
| author_sort | Everson A. Krum |
| collection | DOAJ |
| description | The real mechanism involved in trisomies and leukemogenesis remains unknown and more information about this connection is essential, but unfortunately the clinical outcome and hematological profile of patients with isolated trisomy 11 and AML have not been well characterized. Considering the limited data on the specific disease entity, the current report describes two cases of de novo acute monocytic leukemia (AMoL) and isolated +11, in which this event was further characterized.<br>O mecanismo envolvido em trissomias e leucemogênese permanece não esclarecido e mais dados sobre esta relação são fundamentais, mas infelizmente os resultados clínicos e o perfil hematológico dos pacientes com trissomia 11 isolada e LMA ainda não foram bem caracterizados. Considerando o limitado número de informações, este relato descreve dois casos de leucemia monocítica de novo e trissomia 11 onde este evento foi caracterizado. |
| first_indexed | 2024-12-10T22:31:23Z |
| format | Article |
| id | doaj.art-9622edeebb1d446682c2730e908cf8e6 |
| institution | Directory Open Access Journal |
| issn | 1516-8484 1806-0870 |
| language | English |
| last_indexed | 2024-12-10T22:31:23Z |
| publishDate | 2008-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Revista Brasileira de Hematologia e Hemoterapia |
| spelling | doaj.art-9622edeebb1d446682c2730e908cf8e62022-12-22T01:31:02ZengElsevierRevista Brasileira de Hematologia e Hemoterapia1516-84841806-08702008-01-0130325325510.1590/S1516-84842008000300016Isolated trisomy 11 in de novo acute myeloid leukemia Trissomia 11 isolada em leucemia mielóide aguda de novoEverson A. KrumTatiane HamedMihoko YamamotoMaria de Lourdes ChauffailleThe real mechanism involved in trisomies and leukemogenesis remains unknown and more information about this connection is essential, but unfortunately the clinical outcome and hematological profile of patients with isolated trisomy 11 and AML have not been well characterized. Considering the limited data on the specific disease entity, the current report describes two cases of de novo acute monocytic leukemia (AMoL) and isolated +11, in which this event was further characterized.<br>O mecanismo envolvido em trissomias e leucemogênese permanece não esclarecido e mais dados sobre esta relação são fundamentais, mas infelizmente os resultados clínicos e o perfil hematológico dos pacientes com trissomia 11 isolada e LMA ainda não foram bem caracterizados. Considerando o limitado número de informações, este relato descreve dois casos de leucemia monocítica de novo e trissomia 11 onde este evento foi caracterizado.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842008000300016Trissomia 11leucemia mielóide agudacromossomosTrisomy 11acute myeloid leukemiachromosomes |
| spellingShingle | Everson A. Krum Tatiane Hamed Mihoko Yamamoto Maria de Lourdes Chauffaille Isolated trisomy 11 in de novo acute myeloid leukemia Trissomia 11 isolada em leucemia mielóide aguda de novo Revista Brasileira de Hematologia e Hemoterapia Trissomia 11 leucemia mielóide aguda cromossomos Trisomy 11 acute myeloid leukemia chromosomes |
| title | Isolated trisomy 11 in de novo acute myeloid leukemia Trissomia 11 isolada em leucemia mielóide aguda de novo |
| title_full | Isolated trisomy 11 in de novo acute myeloid leukemia Trissomia 11 isolada em leucemia mielóide aguda de novo |
| title_fullStr | Isolated trisomy 11 in de novo acute myeloid leukemia Trissomia 11 isolada em leucemia mielóide aguda de novo |
| title_full_unstemmed | Isolated trisomy 11 in de novo acute myeloid leukemia Trissomia 11 isolada em leucemia mielóide aguda de novo |
| title_short | Isolated trisomy 11 in de novo acute myeloid leukemia Trissomia 11 isolada em leucemia mielóide aguda de novo |
| title_sort | isolated trisomy 11 in de novo acute myeloid leukemia trissomia 11 isolada em leucemia mieloide aguda de novo |
| topic | Trissomia 11 leucemia mielóide aguda cromossomos Trisomy 11 acute myeloid leukemia chromosomes |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842008000300016 |
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