Correlation between chest CT scores and clinical impact in patients re-infected with COVID-19 during the two attacks: an observational study
Abstract Background Worldwide, millions of people got COVID-19 infection since the start of the pandemic with a large number of deaths. Re-infection with SARS-CoV-2 is possible, because it can mutate into new strains as it is an RNA virus. The main objective of our study is to correlate between CT s...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
SpringerOpen
2022-03-01
|
| Series: | The Egyptian Journal of Radiology and Nuclear Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43055-022-00739-7 |
| _version_ | 1819236843718180864 |
|---|---|
| author | Mona Mohammed Fatouh Nour Mohamed Kandil Nermeen Mahmoud EL Garhy |
| author_facet | Mona Mohammed Fatouh Nour Mohamed Kandil Nermeen Mahmoud EL Garhy |
| author_sort | Mona Mohammed Fatouh |
| collection | DOAJ |
| description | Abstract Background Worldwide, millions of people got COVID-19 infection since the start of the pandemic with a large number of deaths. Re-infection with SARS-CoV-2 is possible, because it can mutate into new strains as it is an RNA virus. The main objective of our study is to correlate between CT severity score of the patients re-infected with COVID-19 during the first and second attack and its clinical impact. Results We performed a retrospective cohort study. It was carried out on fifty symptomatic patients (11 females and 39 males). Their ages ranged from 38 to 71 years. We included only patients who were re-infected after more than 6 months of the first infection and showed clinical symptoms with SARS-CoV-2 PCR-positive test. We found that CT severity score was decreased in the second infection in 47 (94%) of our patients associated with decreased respiratory distress as well as oxygen requirements, while the CT severity score was increased in two patients and only one patient showed no change in CT score severity between two infections. Conclusion The reduction in CT severity score in the majority of re-infected patients suggested the role of the immunity developed from first infection in protection against severe lung affection in case of repeated infection even after 6 months despite poor immunity against re-infection. |
| first_indexed | 2024-12-23T13:10:53Z |
| format | Article |
| id | doaj.art-96236ba5a2f74f4eb27da382295a4393 |
| institution | Directory Open Access Journal |
| issn | 2090-4762 |
| language | English |
| last_indexed | 2024-12-23T13:10:53Z |
| publishDate | 2022-03-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Radiology and Nuclear Medicine |
| spelling | doaj.art-96236ba5a2f74f4eb27da382295a43932022-12-21T17:45:44ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine2090-47622022-03-0153111310.1186/s43055-022-00739-7Correlation between chest CT scores and clinical impact in patients re-infected with COVID-19 during the two attacks: an observational studyMona Mohammed Fatouh0Nour Mohamed Kandil1Nermeen Mahmoud EL Garhy2Radiology Department, Faculty of Medicine, Cairo UniversityRadiology Department, Faculty of Medicine, Cairo UniversityRadiology Department, Faculty of Medicine, Cairo UniversityAbstract Background Worldwide, millions of people got COVID-19 infection since the start of the pandemic with a large number of deaths. Re-infection with SARS-CoV-2 is possible, because it can mutate into new strains as it is an RNA virus. The main objective of our study is to correlate between CT severity score of the patients re-infected with COVID-19 during the first and second attack and its clinical impact. Results We performed a retrospective cohort study. It was carried out on fifty symptomatic patients (11 females and 39 males). Their ages ranged from 38 to 71 years. We included only patients who were re-infected after more than 6 months of the first infection and showed clinical symptoms with SARS-CoV-2 PCR-positive test. We found that CT severity score was decreased in the second infection in 47 (94%) of our patients associated with decreased respiratory distress as well as oxygen requirements, while the CT severity score was increased in two patients and only one patient showed no change in CT score severity between two infections. Conclusion The reduction in CT severity score in the majority of re-infected patients suggested the role of the immunity developed from first infection in protection against severe lung affection in case of repeated infection even after 6 months despite poor immunity against re-infection.https://doi.org/10.1186/s43055-022-00739-7COVID-19CT chestRe-infectionCT severity score |
| spellingShingle | Mona Mohammed Fatouh Nour Mohamed Kandil Nermeen Mahmoud EL Garhy Correlation between chest CT scores and clinical impact in patients re-infected with COVID-19 during the two attacks: an observational study The Egyptian Journal of Radiology and Nuclear Medicine COVID-19 CT chest Re-infection CT severity score |
| title | Correlation between chest CT scores and clinical impact in patients re-infected with COVID-19 during the two attacks: an observational study |
| title_full | Correlation between chest CT scores and clinical impact in patients re-infected with COVID-19 during the two attacks: an observational study |
| title_fullStr | Correlation between chest CT scores and clinical impact in patients re-infected with COVID-19 during the two attacks: an observational study |
| title_full_unstemmed | Correlation between chest CT scores and clinical impact in patients re-infected with COVID-19 during the two attacks: an observational study |
| title_short | Correlation between chest CT scores and clinical impact in patients re-infected with COVID-19 during the two attacks: an observational study |
| title_sort | correlation between chest ct scores and clinical impact in patients re infected with covid 19 during the two attacks an observational study |
| topic | COVID-19 CT chest Re-infection CT severity score |
| url | https://doi.org/10.1186/s43055-022-00739-7 |
| work_keys_str_mv | AT monamohammedfatouh correlationbetweenchestctscoresandclinicalimpactinpatientsreinfectedwithcovid19duringthetwoattacksanobservationalstudy AT nourmohamedkandil correlationbetweenchestctscoresandclinicalimpactinpatientsreinfectedwithcovid19duringthetwoattacksanobservationalstudy AT nermeenmahmoudelgarhy correlationbetweenchestctscoresandclinicalimpactinpatientsreinfectedwithcovid19duringthetwoattacksanobservationalstudy |