Efficacy of high-intensity focused ultrasound cycloplasty in glaucoma and its influencing factor

AIM: To evaluate the efficacy of high-intensity focused ultrasound cyclo plasty(UCP)in the treatment of glaucoma and to investigate related influencing factors.METHODS: The study involved a total of 110 patients(134 eyes)who received UCP treatment between January 2019 and January 2022 at three medic...

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Main Authors: Tang Yurong, Li Fuhua, He Xiangge, Zhou Xiaohong, Zhou Yi, Wang Wei
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2024-04-01
Series:Guoji Yanke Zazhi
Subjects:
Online Access:http://ies.ijo.cn/cn_publish/2024/4/202404023.pdf
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author Tang Yurong
Li Fuhua
He Xiangge
Zhou Xiaohong
Zhou Yi
Wang Wei
author_facet Tang Yurong
Li Fuhua
He Xiangge
Zhou Xiaohong
Zhou Yi
Wang Wei
author_sort Tang Yurong
collection DOAJ
description AIM: To evaluate the efficacy of high-intensity focused ultrasound cyclo plasty(UCP)in the treatment of glaucoma and to investigate related influencing factors.METHODS: The study involved a total of 110 patients(134 eyes)who received UCP treatment between January 2019 and January 2022 at three medical centers: Tianjin Eye Aier Eye Hospital, Chongqing Aier Eye Hospital, and Chongqing Nanping Aier Eye Hospital. Patients were classified into three categories: primary angle-closure glaucoma, primary open-angle glaucoma, and secondary glaucoma. Best corrected visual acuity, intraocular pressure, and the usage of anti-glaucoma medications, etc., were recorded at 6 and 12 mo postoperatively.RESULTS: After 6 months of the UCP procedure, statistically significant differences in intraocular pressure were observed across all groups(all P<0.05). At 12 mo postoperatively, intraocular pressure of the primary angle-closure and primary open-angle glaucoma groups showed differences(all P<0.05). Notably, there were no significant changes in visual acuity at either the 6 or 12 mo compared to preoperative values across all patient groups(all P>0.05). Furthermore, the study identified a statistically significant correlation between the changes in intraocular pressure at 6 mo and factors such as age, history of previous glaucoma surgery, baseline white-to-white(corneal diameter), and the extent of UCP treatment(all P<0.05).CONCLUSION: The UCP procedure has been demonstrated to effectively lower intraocular pressure in patients with glaucoma. The efficacy appears to be influenced by variables including patient age, previous glaucoma surgery history, baseline white-to-white(corneal diameter), and the scope of UCP treatment. Importantly, UCP treatment did not adversely affect visual acuity, underscoring its favorable safety profile.
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spelling doaj.art-96246e4686924fe09c5039a312d98edb2024-03-22T03:14:27ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51232024-04-0124461862210.3980/j.issn.1672-5123.2024.4.23202404023Efficacy of high-intensity focused ultrasound cycloplasty in glaucoma and its influencing factorTang Yurong0Li Fuhua1He Xiangge2Zhou Xiaohong3Zhou Yi4Wang Wei5Chongqing Nanping Aier Eye Hospital, Chongqing 400060, ChinaTianjin Aier Eye Hospital, Tianjin 300190, ChinaChongqing Aier Eye Hospital, Chongqing 400020, ChinaChongqing Nanping Aier Eye Hospital, Chongqing 400060, ChinaChongqing Aier Eye Hospital, Chongqing 400020, ChinaChongqing Aier Eye Hospital, Chongqing 400020, ChinaAIM: To evaluate the efficacy of high-intensity focused ultrasound cyclo plasty(UCP)in the treatment of glaucoma and to investigate related influencing factors.METHODS: The study involved a total of 110 patients(134 eyes)who received UCP treatment between January 2019 and January 2022 at three medical centers: Tianjin Eye Aier Eye Hospital, Chongqing Aier Eye Hospital, and Chongqing Nanping Aier Eye Hospital. Patients were classified into three categories: primary angle-closure glaucoma, primary open-angle glaucoma, and secondary glaucoma. Best corrected visual acuity, intraocular pressure, and the usage of anti-glaucoma medications, etc., were recorded at 6 and 12 mo postoperatively.RESULTS: After 6 months of the UCP procedure, statistically significant differences in intraocular pressure were observed across all groups(all P<0.05). At 12 mo postoperatively, intraocular pressure of the primary angle-closure and primary open-angle glaucoma groups showed differences(all P<0.05). Notably, there were no significant changes in visual acuity at either the 6 or 12 mo compared to preoperative values across all patient groups(all P>0.05). Furthermore, the study identified a statistically significant correlation between the changes in intraocular pressure at 6 mo and factors such as age, history of previous glaucoma surgery, baseline white-to-white(corneal diameter), and the extent of UCP treatment(all P<0.05).CONCLUSION: The UCP procedure has been demonstrated to effectively lower intraocular pressure in patients with glaucoma. The efficacy appears to be influenced by variables including patient age, previous glaucoma surgery history, baseline white-to-white(corneal diameter), and the scope of UCP treatment. Importantly, UCP treatment did not adversely affect visual acuity, underscoring its favorable safety profile.http://ies.ijo.cn/cn_publish/2024/4/202404023.pdfhigh-intensity focused ultrasound ciliary plastyglaucomaefficacyinfluencing factors
spellingShingle Tang Yurong
Li Fuhua
He Xiangge
Zhou Xiaohong
Zhou Yi
Wang Wei
Efficacy of high-intensity focused ultrasound cycloplasty in glaucoma and its influencing factor
Guoji Yanke Zazhi
high-intensity focused ultrasound ciliary plasty
glaucoma
efficacy
influencing factors
title Efficacy of high-intensity focused ultrasound cycloplasty in glaucoma and its influencing factor
title_full Efficacy of high-intensity focused ultrasound cycloplasty in glaucoma and its influencing factor
title_fullStr Efficacy of high-intensity focused ultrasound cycloplasty in glaucoma and its influencing factor
title_full_unstemmed Efficacy of high-intensity focused ultrasound cycloplasty in glaucoma and its influencing factor
title_short Efficacy of high-intensity focused ultrasound cycloplasty in glaucoma and its influencing factor
title_sort efficacy of high intensity focused ultrasound cycloplasty in glaucoma and its influencing factor
topic high-intensity focused ultrasound ciliary plasty
glaucoma
efficacy
influencing factors
url http://ies.ijo.cn/cn_publish/2024/4/202404023.pdf
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AT zhouxiaohong efficacyofhighintensityfocusedultrasoundcycloplastyinglaucomaanditsinfluencingfactor
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