Bone Marrow Stromal Cell-Derived IL-8 Upregulates PVR Expression on Multiple Myeloma Cells via NF-kB Transcription Factor

Bone Marrow Stromal Cell-Derived IL-8 Upregulates PVR Expression on Multiple Myeloma Cells via NF-kB Transcription Factor

Bone marrow stromal cells (BMSCs) strongly contribute to multiple myeloma (MM) progression, promoting the survival and growth of malignant plasma cells (PCs). However, the possible impact of these cells on the immune-mediated recognition of MM cells remains largely unknown. DNAM-1 activating recepto...

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Bibliographic Details
Main Authors: Abdelilah Mekhloufi, Andrea Kosta, Helena Stabile, Rosa Molfetta, Alessandra Zingoni, Alessandra Soriani, Marco Cippitelli, Rossella Paolini, Angela Gismondi, Maria Rosaria Ricciardi, Maria Teresa Petrucci, Laura Masuelli, Giulio Caracciolo, Sara Palchetti, Angela Santoni, Cinzia Fionda
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Cancers
Subjects:
pvr
multiple myeloma
natural killer cells
il-8
bone marrow stromal cells
Online Access:https://www.mdpi.com/2072-6694/12/2/440

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