1,3-Indanedione: An versatile building block
Indanone-containing compounds are very important components of various natural products, chemical drugs, agrochemicals and functionalized material fields. 1,3-Indanedione is a typical cyclic 1,3-dicarbonyl compound with three contiguous reactive electrophilic and nucleophilic sites. The easily prepa...
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| Format: | Article |
| Language: | English |
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KeAi Communications Co. Ltd.
2023-05-01
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| Series: | Green Synthesis and Catalysis |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666554922001338 |
| _version_ | 1797809791684313088 |
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| author | Chaoguo Yan |
| author_facet | Chaoguo Yan |
| author_sort | Chaoguo Yan |
| collection | DOAJ |
| description | Indanone-containing compounds are very important components of various natural products, chemical drugs, agrochemicals and functionalized material fields. 1,3-Indanedione is a typical cyclic 1,3-dicarbonyl compound with three contiguous reactive electrophilic and nucleophilic sites. The easily prepared 2-arylidene-1,3-indanediones are active α,β-unsaturated carbonyl compounds and could act as 1,3-dipolarophile, 1,4-dienophile and 1-oxa-1,3-diene, etc. On the other hand, the homodimer (bindone) and cyclotrimer (truxenone) derived from base-catalyzed self-condensation of 1,3-indanedione are also reactive carbonyl compounds. Therefore, 1,3-indanedione and its derivatives can be employed as key substrates in various domino and multicomponent reactions. In this review, we summarized the recent progress on the domino and multicomponent reactions of 1,3-indanedione, especially on our achievements on the synthetic applications for the complex indanone-containing carbocyclic and heterocyclic compounds. |
| first_indexed | 2024-03-13T06:58:06Z |
| format | Article |
| id | doaj.art-9626159b72f44ea38a491971876dc768 |
| institution | Directory Open Access Journal |
| issn | 2666-5549 |
| language | English |
| last_indexed | 2024-03-13T06:58:06Z |
| publishDate | 2023-05-01 |
| publisher | KeAi Communications Co. Ltd. |
| record_format | Article |
| series | Green Synthesis and Catalysis |
| spelling | doaj.art-9626159b72f44ea38a491971876dc7682023-06-07T04:49:55ZengKeAi Communications Co. Ltd.Green Synthesis and Catalysis2666-55492023-05-014278881,3-Indanedione: An versatile building blockChaoguo Yan0College of Chemistry & Chemical Engineering, Yangzhou University, Yangzhou 225002, ChinaIndanone-containing compounds are very important components of various natural products, chemical drugs, agrochemicals and functionalized material fields. 1,3-Indanedione is a typical cyclic 1,3-dicarbonyl compound with three contiguous reactive electrophilic and nucleophilic sites. The easily prepared 2-arylidene-1,3-indanediones are active α,β-unsaturated carbonyl compounds and could act as 1,3-dipolarophile, 1,4-dienophile and 1-oxa-1,3-diene, etc. On the other hand, the homodimer (bindone) and cyclotrimer (truxenone) derived from base-catalyzed self-condensation of 1,3-indanedione are also reactive carbonyl compounds. Therefore, 1,3-indanedione and its derivatives can be employed as key substrates in various domino and multicomponent reactions. In this review, we summarized the recent progress on the domino and multicomponent reactions of 1,3-indanedione, especially on our achievements on the synthetic applications for the complex indanone-containing carbocyclic and heterocyclic compounds.http://www.sciencedirect.com/science/article/pii/S26665549220013381,3-IndanedioneBindoneIndeno[1,2-a]fluorineDomino reactionMulticomponent reaction |
| spellingShingle | Chaoguo Yan 1,3-Indanedione: An versatile building block Green Synthesis and Catalysis 1,3-Indanedione Bindone Indeno[1,2-a]fluorine Domino reaction Multicomponent reaction |
| title | 1,3-Indanedione: An versatile building block |
| title_full | 1,3-Indanedione: An versatile building block |
| title_fullStr | 1,3-Indanedione: An versatile building block |
| title_full_unstemmed | 1,3-Indanedione: An versatile building block |
| title_short | 1,3-Indanedione: An versatile building block |
| title_sort | 1 3 indanedione an versatile building block |
| topic | 1,3-Indanedione Bindone Indeno[1,2-a]fluorine Domino reaction Multicomponent reaction |
| url | http://www.sciencedirect.com/science/article/pii/S2666554922001338 |
| work_keys_str_mv | AT chaoguoyan 13indanedioneanversatilebuildingblock |