Long-term calcium imaging reveals functional development in hiPSC-derived cultures comparable to human but not rat primary cultures

Long-term calcium imaging reveals functional development in hiPSC-derived cultures comparable to human but not rat primary cultures

Summary: Models for human brain-oriented research are often established on primary cultures from rodents, which fails to recapitulate cellular specificity and molecular cues of the human brain. Here we investigated whether neuronal cultures derived from human induced pluripotent stem cells (hiPSCs)...

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Bibliographic Details
Main Authors: Estefanía Estévez-Priego, Martina Moreno-Fina, Emanuela Monni, Zaal Kokaia, Jordi Soriano, Daniel Tornero
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Stem Cell Reports
Subjects:
neural stem cells
neuronal networks
human cellular models
calcium imaging
functional connectivity
human iPSCs
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671122005471

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