Efficient Stereo-Selective Fluorination on Vitamin D<sub>3</sub> Side-Chain Using Electrophilic Fluorination

Efficient Stereo-Selective Fluorination on Vitamin D<sub>3</sub> Side-Chain Using Electrophilic Fluorination

Our research regarding side-chain fluorinated vitamin D<sub>3</sub> analogues has explored a series of efficient fluorination methods. In this study, a new electrophilic stereo-selective fluorination methodology at C24 and C22 positions of the vitamin D<sub>3</sub> side-chain...

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Bibliographic Details
Main Authors: Fumihiro Kawagoe, Sayuri Mototani, Atsushi Kittaka
Format: Article
Language:English
Published: MDPI AG 2023-12-01
Series:Biomolecules
Subjects:
electrophilic fluorination
<i>N</i>-fluorobenzenesulfonimide (NFSI)
side-chain fluorinated vitamin D<sub>3</sub>
side-chain
Evans chiral auxiliary
Online Access:https://www.mdpi.com/2218-273X/14/1/37

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